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Every dated change on the records linked to Cancer of unknown primary, favourable subsets, newest first: approvals and regulatory steps on its medicines, trials that reported, guideline versions, milestones, and when this page itself was checked. Dates come from the records; none is inferred. Orientation, not medical advice.
Treat as node-positive breast cancer: axillary dissection, breast radiotherapy or mastectomy, systemic therapy by receptor status.
Treat as head and neck cancer: HPV and EBV testing, neck dissection or chemoradiotherapy with cisplatin.
Treat as extragonadal germ cell tumour with cisplatin-based combination chemotherapy.
Platinum-etoposide as for extrapulmonary neuroendocrine carcinoma; somatostatin analogues and radioligand therapy for well-differentiated tumours.
Treat as advanced ovarian cancer: cytoreductive surgery and carboplatin-paclitaxel with maintenance as indicated.
Resection or stereotactic radiotherapy with curative intent.
Histology with directed immunohistochemistry, CT of chest, abdomen and pelvis, sex-specific examinations and tumour markers, PET-CT for cervical node squamous carcinoma and single-site disease.
A milestone in how this cancer is treated.