{"slug":"oncolytic-virus","tag":"oncolytic-virus","variants":["oncolytic-virus"],"description":"No description yet","count":8,"kinds":{"person":8},"related":[{"slug":"immunotherapy","tag":"immunotherapy","shared":3},{"slug":"croatia","tag":"croatia","shared":2},{"slug":"neuro-oncology","tag":"neuro-oncology","shared":2},{"slug":"virology","tag":"virology","shared":2},{"slug":"canada","tag":"canada","shared":1},{"slug":"japan","tag":"japan","shared":1},{"slug":"liver","tag":"liver","shared":1},{"slug":"melanoma","tag":"melanoma","shared":1},{"slug":"myeloma","tag":"myeloma","shared":1},{"slug":"surgery","tag":"surgery","shared":1}],"records":[{"id":"howard-kaufman","kind":"person","name":"Howard L. Kaufman","route":"/people/howard-kaufman/","tldr":"Led OPTiM, the trial that made talimogene laherparepvec the first approved oncolytic virus therapy."},{"id":"yuman-fong","kind":"person","name":"Yuman Fong","route":"/people/yuman-fong/","tldr":"Liver surgeon who defined who benefits from resecting colorectal liver metastases and pioneered oncolytic virus therapy."},{"id":"beata-halassy","kind":"person","name":"Beata Halassy","route":"/people/beata-halassy/","tldr":"Beata Halassy is a Croatian virologist who grows and characterises viruses, and is the senior author of a 2024 case report of self-experimental oncolytic virotherapy."},{"id":"dubravko-forcic","kind":"person","name":"Dubravko Forcic","route":"/people/dubravko-forcic/","tldr":"Dubravko Forcic is a Croatian virologist who works on vaccine virus strains and was joint first author of the 2024 self-experimental oncolytic virotherapy case report."},{"id":"stephen-russell","kind":"person","name":"Stephen J. Russell","route":"/people/stephen-russell/","tldr":"Stephen Russell built the engineered measles viruses used against cancer and reported the case in which one intravenous dose put a patient's myeloma into complete remission."},{"id":"john-bell","kind":"person","name":"John C. Bell","route":"/people/john-bell/","tldr":"John Bell's laboratory showed that cancer cells which have broken their interferon alarm cannot defend themselves against a virus, the mechanism the whole field is built on."},{"id":"robert-martuza","kind":"person","name":"Robert L. Martuza","route":"/people/robert-martuza/","tldr":"Robert Martuza built the first genetically engineered virus designed to treat a cancer, a herpes virus crippled so that it could only replicate in dividing tumour cells."},{"id":"tomoki-todo","kind":"person","name":"Tomoki Todo","route":"/people/tomoki-todo/","tldr":"Tomoki Todo built the triple-mutated herpes virus that became the first oncolytic virus approved in Japan, and ran the trial in recurrent glioblastoma behind that approval."}]}