{"slug":"epigenetics","tag":"epigenetics","variants":["epigenetics"],"description":"No description yet","count":4,"kinds":{"person":3,"technology":1},"related":[{"slug":"clinician-scientist","tag":"clinician-scientist","shared":2},{"slug":"biological-ageing","tag":"biological-ageing","shared":1},{"slug":"biomarker","tag":"biomarker","shared":1},{"slug":"breast-cancer","tag":"breast cancer","shared":1},{"slug":"france","tag":"france","shared":1},{"slug":"leadership","tag":"leadership","shared":1},{"slug":"mds","tag":"mds","shared":1},{"slug":"prostate-cancer","tag":"prostate cancer","shared":1},{"slug":"rejuvenation","tag":"rejuvenation","shared":1},{"slug":"survivorship","tag":"survivorship","shared":1}],"records":[{"id":"bradley-cairns","kind":"person","name":"Bradley Cairns","route":"/people/bradley-cairns/","tldr":"Epigenetics researcher who became CEO of Huntsman Cancer Institute at the University of Utah in September 2025."},{"id":"susan-clark","kind":"person","name":"Susan Clark","route":"/people/susan-clark/","tldr":"Pioneer of DNA methylation analysis whose Garvan laboratory studies how epigenetic changes drive prostate and breast cancer."},{"id":"pierre-fenaux","kind":"person","name":"Pierre Fenaux","route":"/people/pierre-fenaux/","tldr":"Led AZA-001, which showed azacitidine extends survival in high-risk MDS and made hypomethylating agents standard."},{"id":"rejuv-age-epigenetic-clocks","kind":"technology","name":"Epigenetic age after cancer treatment","route":"/technologies/rejuv-age-epigenetic-clocks/","status":"emerging","tldr":"An epigenetic clock reads chemical marks on DNA and estimates how old the body looks, which is not always the age on a birth certificate. In survivors of childhood cancer the clock runs ahead of chronological age, and the gap is larger after radiotherapy and after certain chemotherapy drugs. What the gap means for any one person is not yet known, and the clocks do not agree with each other."}]}