{"slug":"cancer-biology","tag":"cancer-biology","variants":["cancer-biology","cancer biology"],"description":"No description yet","count":8,"kinds":{"person":8},"related":[{"slug":"clinician-scientist","tag":"clinician-scientist","shared":4},{"slug":"leadership","tag":"leadership","shared":4},{"slug":"scientist","tag":"scientist","shared":4},{"slug":"nobel-laureate","tag":"nobel-laureate","shared":2},{"slug":"colorectal-cancer","tag":"colorectal cancer","shared":1},{"slug":"drug-development","tag":"drug development","shared":1},{"slug":"liver-cancer","tag":"liver cancer","shared":1},{"slug":"organoids","tag":"organoids","shared":1}],"records":[{"id":"lars-zender","kind":"person","name":"Lars Zender","route":"/people/lars-zender/","tldr":"Medical oncologist and cancer biologist at Tübingen, known for work on senescence surveillance and functional genomics in liver cancer."},{"id":"patrick-mehlen","kind":"person","name":"Patrick Mehlen","route":"/people/patrick-mehlen/","tldr":"Cancer biologist who discovered the dependence-receptor concept and took netrin-1 blockade from bench to clinical trials at Centre Léon Bérard."},{"id":"florian-greten","kind":"person","name":"Florian R. Greten","route":"/people/florian-greten/","tldr":"Tumour biologist known for linking inflammation to cancer, directing the Georg-Speyer-Haus within UCT Frankfurt."},{"id":"senthil-muthuswamy","kind":"person","name":"Senthil K. Muthuswamy","route":"/people/senthil-muthuswamy/","tldr":"Cancer biologist who directs the National Cancer Institute's Center for Cancer Research, the large intramural research programme in Bethesda."},{"id":"yosef-yarden","kind":"person","name":"Yosef Yarden","route":"/people/yosef-yarden/","tldr":"One of the people who worked out what the HER family of receptors does and how antibodies against them behave, including why combining two antibodies against the same receptor works better than either alone."},{"id":"moshe-oren","kind":"person","name":"Moshe Oren","route":"/people/moshe-oren/","tldr":"Cloned p53 and then spent a career on what it does. The field's first reading of his own 1984 result, that p53 was an oncogene, turned out to be wrong, and the correction is the better story."},{"id":"aaron-ciechanover","kind":"person","name":"Aaron Ciechanover","route":"/people/aaron-ciechanover/","tldr":"Shared the 2004 Nobel Prize in Chemistry for discovering how cells label proteins for destruction. That labelling system is what proteasome inhibitors block and what every protein degrader hijacks."},{"id":"avram-hershko","kind":"person","name":"Avram Hershko","route":"/people/avram-hershko/","tldr":"Shared the 2004 Nobel Prize in Chemistry for the discovery of ubiquitin-mediated protein degradation, and still works on how the machinery that destroys proteins controls cell division."}]}