# OnCo record common-rule (term). Data CC BY-NC 4.0, attribute "Data from OnCo (onco.cc)". Whole corpus: https://onco.cc/api/v1/onco.nt
@prefix schema: <https://schema.org/> .
@prefix onco: <https://onco.cc/ns#> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

<https://onco.cc/terms/common-rule/>
  a schema:DefinedTerm ;
  onco:kind "term" ;
  schema:identifier "common-rule" ;
  schema:name "The Common Rule (45 CFR 46)"@en ;
  schema:alternateName "Common Rule"@en, "45 CFR 46"@en, "Federal Policy for the Protection of Human Subjects"@en, "revised Common Rule"@en, "institutional review board"@en, "IRB"@en, "single IRB"@en, "broad consent"@en, "21 CFR 50"@en, "21 CFR 56"@en ;
  schema:description "The US rules that require an ethics committee to approve research on people and require informed consent, written in 1991 and rewritten in 2018 so that a single committee can oversee a multi-site cancer trial and patients can give broad consent for future use of their samples."@en ;
  schema:url <https://onco.cc/terms/common-rule/> ;
  schema:dateModified "2026-09-17"^^xsd:date ;
  schema:sameAs <https://en.wikipedia.org/wiki/Common_Rule> ;
  schema:citation <https://en.wikipedia.org/wiki/Common_Rule>, <https://www.hhs.gov/ohrp/regulations-and-policy/regulations/45-cfr-46/index.html>, <https://www.ecfr.gov/current/title-21/chapter-I/subchapter-A/part-50> ;
  onco:tag "law", "us" ;
  onco:related <https://onco.cc/terms/declaration-of-helsinki/>, <https://onco.cc/terms/ich-gcp/>, <https://onco.cc/terms/hipaa/>, <https://onco.cc/terms/clinical-trial/>, <https://onco.cc/terms/eu-clinical-trials-regulation/>, <https://onco.cc/terms/fdca/>, <https://onco.cc/terms/gina/> ;
  onco:bottlenecks <https://onco.cc/bottlenecks/b-trial-enrolment/>, <https://onco.cc/bottlenecks/b-data-silos/> .