{"entity":{"id":"zhang-fangliang","kind":"person","name":"Fangliang (Frank) Zhang","aka":["Frank Zhang","张方亮"],"tldr":"Frank Zhang founded GenScript and its cell therapy spin-out Legend Biotech, whose Nanjing team invented the myeloma CAR-T that became Carvykti.","summary":"Zhang founded GenScript in New Jersey in 2002 and moved it to Nanjing; Legend Biotech, spun out in 2014, developed the llama-derived BCMA CAR-T LCAR-B38M (LEGEND-2), partnered it with Janssen in 2017 and listed on Nasdaq in 2020; ciltacabtagene autoleucel was approved by the FDA in 2022 and the NMPA in 2024. He stepped back from executive roles in 2021.","asOf":"2026-09-10","links":[{"label":"Legend Biotech","url":"https://www.legendbiotech.com/"}],"tags":["china"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":["ciltacabtagene-autoleucel"],"companies":["legend-biotech"],"institutions":[],"pathways":[],"terms":[],"trials":["legend-2","cartitude-1"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Founder and former Chairman, Legend Biotech; former Chairman, GenScript Biotech","specialisms":["Cell therapy","Biotech leadership","Gene synthesis"],"profiles":[{"label":"Legend Biotech","url":"https://www.legendbiotech.com/"}],"papers":[]},"route":"/people/zhang-fangliang/","neighbours":{"drug":[{"id":"ciltacabtagene-autoleucel","kind":"drug","name":"Ciltacabtagene autoleucel","route":"/drugs/ciltacabtagene-autoleucel/"}],"company":[{"id":"legend-biotech","kind":"company","name":"Legend Biotech","route":"/companies/legend-biotech/"}],"trial":[{"id":"cartitude-1","kind":"trial","name":"CARTITUDE-1","route":"/trials/cartitude-1/"},{"id":"legend-2","kind":"trial","name":"LEGEND-2","route":"/trials/legend-2/"}]}}