{"entity":{"id":"zap-surgical-systems","kind":"company","name":"ZAP Surgical Systems","aka":[],"tldr":"ZAP Surgical makes ZAP-X, a self-shielded radiosurgery machine that aims beams from thousands of angles at brain tumours, treating brain metastases and meningiomas in one to five outpatient sessions without the concrete bunker or cobalt-60 source that older systems need. It is cleared in the US, Japan and Europe, with installations including Gustave Roussy.","summary":"ZAP Surgical Systems, founded by Stanford neurosurgeon John R. Adler, makes the ZAP-X Gyroscopic Radiosurgery platform for dedicated cranial stereotactic radiosurgery (SRS). A linear accelerator on dual independent gantries delivers non-coplanar beams from thousands of angles with integrated kV imaging. The self-shielded design needs no radiation vault and, unlike Gamma Knife, no cobalt-60 source, lowering cost and allowing installation in outpatient settings. Indications include brain metastases, meningiomas and trigeminal neuralgia, treated in one to five sessions. ZAP-X received FDA 510(k) clearance in 2017, Japan Shonin clearance in 2020 and CE marking in 2021; the ZAP-Axon planning system is also FDA and CE cleared. Installations include Gustave Roussy, Haaglanden Medical Center, several German hospitals and eight systems in China. In November 2024 the company closed a USD 78 million Series E led by Qingdao Baheal Medical.","asOf":"2026-09-10","links":[{"label":"Official website","url":"https://zapsurgical.com/"},{"label":"Series E press release (Nov 2024)","url":"https://zapsurgical.com/news/zap-surgical-secures-funding/"},{"label":"Newsroom","url":"https://zapsurgical.com/newsroom/"},{"label":"Contact page (global headquarters, San Carlos)","url":"https://zapsurgical.com/contact/"}],"tags":[],"related":[],"cancers":[],"sections":["radiation","devices"],"technologies":["sbrt","imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["Founding year and earlier rounds (Series A to D) are unsourced and omitted. The 3 MV linac detail comes from general product knowledge and is not in the fetched pages; treat as unverified."],"hq":"San Carlos, CA","country":"US","companyType":"devices","website":"https://zapsurgical.com/","stage":"growth","investors":[],"funding":[{"round":"Series E","year":2024,"amountUsd":78000000,"source":"https://zapsurgical.com/news/zap-surgical-secures-funding/","note":"Led by Qingdao Baheal Medical with participation from other strategic investors"}]},"route":"/companies/zap-surgical-systems/","neighbours":{"section":[{"id":"devices","kind":"section","name":"Devices & Physical Therapies","route":"/fronts/devices/"},{"id":"radiation","kind":"section","name":"Radiation Therapy","route":"/fronts/radiation/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"},{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"},{"id":"radiosurgery-srs","kind":"technology","name":"Stereotactic radiosurgery (Gamma Knife, CyberKnife, linac SRS)","route":"/technologies/radiosurgery-srs/"},{"id":"zap-x","kind":"technology","name":"ZAP-X gyroscopic radiosurgery","route":"/technologies/zap-x/"}],"roadmap":[{"id":"devices-roadmap","kind":"roadmap","name":"Devices and physical therapies roadmap: heat and light → electric fields and focused sound → drug-releasing implants","route":"/roadmaps/devices-roadmap/"}]}}