{"entity":{"id":"willemien-van-driel","kind":"person","name":"Willemien J. van Driel","aka":[],"tldr":"Led OVHIPEC-1, the trial that showed heated intraperitoneal chemotherapy at surgery extends survival in ovarian cancer.","summary":"Willemien van Driel was principal investigator of OVHIPEC-1, the Dutch randomised trial showing that adding hyperthermic intraperitoneal cisplatin to interval cytoreductive surgery improves recurrence-free and overall survival in stage III ovarian cancer, the first level-one evidence for HIPEC in the disease. She leads OVHIPEC-2 in the primary surgery setting.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=van%20Driel%20WJ%5BAuthor%5D%20HIPEC%20ovarian"}],"tags":["ovarian","surgery","hipec"],"related":[],"cancers":["ovarian"],"sections":[],"technologies":["hipec"],"targets":[],"drugs":[],"companies":[],"institutions":["nki"],"pathways":[],"terms":[],"trials":["ovhipec-1"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Gynaecologic Oncologist, Netherlands Cancer Institute","institutionId":"nki","specialisms":["Ovarian cancer surgery","HIPEC","Interval cytoreduction"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=van%20Driel%20WJ%5BAuthor%5D%20HIPEC%20ovarian"}],"papers":[{"title":"Hyperthermic intraperitoneal chemotherapy in ovarian cancer (OVHIPEC-1)","journal":"NEJM","year":2018,"doi":"10.1056/NEJMoa1708618"},{"title":"Overall survival after hyperthermic intraperitoneal chemotherapy for ovarian cancer: 10-year follow-up of OVHIPEC-1","journal":"Lancet Oncology","year":2023}],"orcid":"0000-0003-2246-1994"},"route":"/people/willemien-van-driel/","neighbours":{"cancer":[{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"}],"technology":[{"id":"hipec","kind":"technology","name":"HIPEC / PIPAC (intraperitoneal chemotherapy)","route":"/technologies/hipec/"}],"institution":[{"id":"nki","kind":"institution","name":"Netherlands Cancer Institute (NKI-AvL)","route":"/institutions/nki/"}],"trial":[{"id":"ovhipec-1","kind":"trial","name":"OVHIPEC-1","route":"/trials/ovhipec-1/"}]}}