{"entity":{"id":"uclh","kind":"institution","name":"University College London Hospitals / UCL Cancer Institute","aka":["UCLH","UCL Cancer Institute","UCLH Proton Beam Therapy Centre"],"tldr":"Central London's university hospital and one of two NHS proton beam therapy centres, backed by UCL's cancer institute and its CAR-T and lung cancer evolution research.","summary":"UCLH runs one of the UK's largest cancer services, including the University College Hospital Macmillan Cancer Centre, a national proton beam therapy centre that opened in 2021, and a teenage and young adult cancer unit. The UCL Cancer Institute hosts the TRACERx lung cancer evolution study with the Francis Crick Institute under Charles Swanton, Martin Pule's CAR-T engineering group that spun out Autolus, and Sergio Quezada's work on clonal neoantigen T-cell therapy behind Achilles Therapeutics. The MRC Clinical Trials Unit at UCL coordinated the STAMPEDE prostate cancer platform trial and the Cancer Research UK & UCL Cancer Trials Centre runs many national trials. UCLH is also a major site for lung screening studies and adult ALL cell therapy.","asOf":"2026-09-09","links":[{"label":"UCLH cancer services","url":"https://www.uclh.nhs.uk/our-services/find-service/cancer-services"},{"label":"UCL Cancer Institute","url":"https://www.ucl.ac.uk/cancer"},{"label":"Proton beam therapy","url":"https://www.uclh.nhs.uk/our-services/find-service/cancer-services/proton-beam-therapy"},{"label":"PTCOG: particle therapy facilities in operation","url":"https://www.ptcog.site/index.php/facilities-in-operation-public"}],"tags":[],"related":[],"cancers":["nsclc","all-leukemia","prostate","dlbcl","pancreatic","lung-cancer"],"sections":["radiation","cell-therapy"],"technologies":["proton-therapy","car-t","liquid-biopsy","wes-wgs","til-therapy","proton-therapy-systems","gamma-knife","radiosurgery-srs","hifu-histotripsy"],"targets":[],"drugs":[],"companies":[],"institutions":["francis-crick","cruk","great-ormond-street"],"pathways":[],"terms":["ctdna","neoantigen","basket-umbrella-platform"],"trials":["tracerx","summit-lung","lungsearch","promis","transform-prostate","stampede"],"people":["charles-swanton","nicholas-james","david-probert","mark-emberton","jonathan-ledermann","usha-menon","mary-mccormack","mahesh-parmar","caroline-moore"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"London","country":"GB","lat":51.525,"lng":-0.136,"institutionType":"hospital","website":"https://www.uclh.nhs.uk/our-services/find-service/cancer-services","university":"University College London","programs":["Proton beam therapy","TRACERx and cancer evolution","CAR-T engineering","MRC Clinical Trials Unit (STAMPEDE)","Teenage and young adult cancer"]},"route":"/institutions/uclh/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"},{"id":"lung-cancer","kind":"cancer","name":"Lung cancer (all types)","route":"/cancers/lung-cancer/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"section":[{"id":"cell-therapy","kind":"section","name":"Cell Therapy","route":"/fronts/cell-therapy/"},{"id":"radiation","kind":"section","name":"Radiation Therapy","route":"/fronts/radiation/"}],"technology":[{"id":"car-t","kind":"technology","name":"CAR-T cell therapy","route":"/technologies/car-t/"},{"id":"hifu-histotripsy","kind":"technology","name":"Focused ultrasound & histotripsy","route":"/technologies/hifu-histotripsy/"},{"id":"gamma-knife","kind":"technology","name":"Gamma Knife","route":"/technologies/gamma-knife/"},{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"proton-therapy","kind":"technology","name":"Proton therapy","route":"/technologies/proton-therapy/"},{"id":"proton-therapy-systems","kind":"technology","name":"Proton therapy machines: cyclotrons, synchrotrons and single-room systems","route":"/technologies/proton-therapy-systems/"},{"id":"radiosurgery-srs","kind":"technology","name":"Stereotactic radiosurgery (Gamma Knife, CyberKnife, linac SRS)","route":"/technologies/radiosurgery-srs/"},{"id":"til-therapy","kind":"technology","name":"TIL therapy","route":"/technologies/til-therapy/"},{"id":"wes-wgs","kind":"technology","name":"Whole-exome & whole-genome sequencing","route":"/technologies/wes-wgs/"}],"institution":[{"id":"ammf","kind":"institution","name":"AMMF, the Cholangiocarcinoma Charity","route":"/institutions/ammf/"},{"id":"barts-cancer-institute","kind":"institution","name":"Barts Cancer Institute / Barts Health NHS Trust","route":"/institutions/barts-cancer-institute/"},{"id":"cruk","kind":"institution","name":"Cancer Research UK","route":"/institutions/cruk/"},{"id":"cruk-city-of-london-centre","kind":"institution","name":"Cancer Research UK City of London Centre","route":"/institutions/cruk-city-of-london-centre/"},{"id":"great-ormond-street","kind":"institution","name":"Great Ormond Street Hospital for Children","route":"/institutions/great-ormond-street/"},{"id":"north-central-london-cancer-alliance","kind":"institution","name":"North Central London Cancer Alliance","route":"/institutions/north-central-london-cancer-alliance/"},{"id":"francis-crick","kind":"institution","name":"The Francis Crick Institute","route":"/institutions/francis-crick/"}],"term":[{"id":"basket-umbrella-platform","kind":"term","name":"Basket, umbrella, and platform trials","route":"/terms/basket-umbrella-platform/"},{"id":"ctdna","kind":"term","name":"Circulating tumour DNA (ctDNA)","route":"/terms/ctdna/"},{"id":"neoantigen","kind":"term","name":"Neoantigen","route":"/terms/neoantigen/"}],"trial":[{"id":"abc-07","kind":"trial","name":"ABC-07","route":"/trials/abc-07/"},{"id":"abc-12","kind":"trial","name":"ABC-12","route":"/trials/abc-12/"},{"id":"europac","kind":"trial","name":"EUROPAC","route":"/trials/europac/"},{"id":"focus4","kind":"trial","name":"FOCUS4","route":"/trials/focus4/"},{"id":"fort","kind":"trial","name":"FoRT","route":"/trials/fort/"},{"id":"ucl-proton-hemithoracic-mpm","kind":"trial","name":"Hemithoracic irradiation with proton therapy in malignant pleural mesothelioma (UCL)","route":"/trials/ucl-proton-hemithoracic-mpm/"},{"id":"herizon-btc-01","kind":"trial","name":"HERIZON-BTC-01","route":"/trials/herizon-btc-01/"},{"id":"lungsearch","kind":"trial","name":"Lung-SEARCH","route":"/trials/lungsearch/"},{"id":"patch-transdermal-oestradiol","kind":"trial","name":"PATCH (Prostate Adenocarcinoma Transcutaneous Hormone)","route":"/trials/patch-transdermal-oestradiol/"},{"id":"precision-panc","kind":"trial","name":"Precision-Panc","route":"/trials/precision-panc/"},{"id":"promis","kind":"trial","name":"PROMIS","route":"/trials/promis/"},{"id":"quartz","kind":"trial","name":"QUARTZ","route":"/trials/quartz/"},{"id":"radicals-hd","kind":"trial","name":"RADICALS-HD","route":"/trials/radicals-hd/"},{"id":"radicals-rt","kind":"trial","name":"RADICALS-RT","route":"/trials/radicals-rt/"},{"id":"safir-abc10","kind":"trial","name":"SAFIR-ABC10","route":"/trials/safir-abc10/"},{"id":"sevilla","kind":"trial","name":"SEVILLA","route":"/trials/sevilla/"},{"id":"stampede","kind":"trial","name":"STAMPEDE","route":"/trials/stampede/"},{"id":"summit-lung","kind":"trial","name":"SUMMIT (lung health check study)","route":"/trials/summit-lung/"},{"id":"targit-a","kind":"trial","name":"TARGIT-A (targeted intraoperative radiotherapy)","route":"/trials/targit-a/"},{"id":"tracerx","kind":"trial","name":"TRACERx","route":"/trials/tracerx/"},{"id":"transform-prostate","kind":"trial","name":"TRANSFORM","route":"/trials/transform-prostate/"}],"person":[{"id":"caroline-moore","kind":"person","name":"Caroline Moore","route":"/people/caroline-moore/"},{"id":"charles-swanton","kind":"person","name":"Charles Swanton","route":"/people/charles-swanton/"},{"id":"david-probert","kind":"person","name":"David Probert","route":"/people/david-probert/"},{"id":"gerhardt-attard","kind":"person","name":"Gerhardt Attard","route":"/people/gerhardt-attard/"},{"id":"john-bridgewater","kind":"person","name":"John Bridgewater","route":"/people/john-bridgewater/"},{"id":"jonathan-ledermann","kind":"person","name":"Jonathan A. Ledermann","route":"/people/jonathan-ledermann/"},{"id":"mahesh-parmar","kind":"person","name":"Mahesh K. B. Parmar","route":"/people/mahesh-parmar/"},{"id":"mark-emberton","kind":"person","name":"Mark Emberton","route":"/people/mark-emberton/"},{"id":"mary-mccormack","kind":"person","name":"Mary McCormack","route":"/people/mary-mccormack/"},{"id":"nicholas-james","kind":"person","name":"Nicholas James","route":"/people/nicholas-james/"},{"id":"usha-menon","kind":"person","name":"Usha Menon","route":"/people/usha-menon/"}],"collection":[{"id":"uk-hpb-specialist-centres","kind":"collection","name":"UK specialist HPB cancer centres","route":"/collections/uk-hpb-specialist-centres/"}],"paper":[{"id":"paper-ahmed-promis-multiparametric-mri-lancet-2017","kind":"paper","name":"PROMIS: diagnostic accuracy of multiparametric MRI and TRUS biopsy in prostate cancer","route":"/key-papers/paper-ahmed-promis-multiparametric-mri-lancet-2017/"}],"company":[{"id":"mrc-ctu","kind":"company","name":"MRC Clinical Trials Unit at UCL","route":"/companies/mrc-ctu/"}]}}