{"entity":{"id":"trevor-pugh","kind":"person","name":"Trevor J. Pugh","aka":[],"tldr":"Genomicist who applies cell-free DNA and single-cell sequencing to track cancer and immunotherapy response.","summary":"Trevor J. Pugh is a Senior Scientist at the Princess Margaret Cancer Centre and Director of Genomics at the Ontario Institute for Cancer Research. He is a genomicist who applies cell-free DNA and single-cell sequencing to track cancer and immunotherapy response, leading translational genomics programmes on cfDNA methylation, immune repertoire sequencing and clinical trial genomics. His selected paper reports the genetic landscape of high-risk neuroblastoma. He continues to work on liquid biopsy and single-cell and spatial profiling.","asOf":"2026-09-08","links":[{"label":"UHN profile","url":"https://www.uhnresearch.ca/researcher/trevor-j-pugh"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Pugh%20TJ%5BAuthor%5D"}],"tags":[],"related":[],"cancers":["neuroblastoma"],"sections":[],"technologies":["liquid-biopsy","single-cell-spatial"],"targets":[],"drugs":[],"companies":[],"institutions":["princess-margaret"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Senior Scientist, Princess Margaret; Director of Genomics, Ontario Institute for Cancer Research","institutionId":"princess-margaret","specialisms":["Cancer genomics","ctDNA","Single-cell sequencing"],"profiles":[{"label":"UHN profile","url":"https://www.uhnresearch.ca/researcher/trevor-j-pugh"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Pugh%20TJ%5BAuthor%5D"}],"papers":[{"title":"The genetic landscape of high-risk neuroblastoma","journal":"Nature Genetics","year":2013,"url":"https://doi.org/10.1038/ng.2529","doi":"10.1038/ng.2529"}],"orcid":"0000-0002-8073-5888"},"route":"/people/trevor-pugh/","neighbours":{"cancer":[{"id":"neuroblastoma","kind":"cancer","name":"Neuroblastoma (paediatric)","route":"/cancers/neuroblastoma/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"single-cell-spatial","kind":"technology","name":"Single-cell & spatial profiling","route":"/technologies/single-cell-spatial/"}],"institution":[{"id":"oicr","kind":"institution","name":"Ontario Institute for Cancer Research","route":"/institutions/oicr/"},{"id":"princess-margaret","kind":"institution","name":"Princess Margaret Cancer Centre","route":"/institutions/princess-margaret/"}]}}