{"entity":{"id":"the-christie","kind":"institution","name":"The Christie NHS Foundation Trust","aka":[],"tldr":"The Christie is Europe's largest single-site cancer centre and the UK's first NHS proton therapy centre.","summary":"The Christie NHS Foundation Trust in Manchester is Europe's largest single-site cancer centre and the first NHS proton beam therapy centre, opened in 2018; it ranks twenty-third in the Newsweek/Statista oncology list and is tied to the University of Manchester. It runs one of the largest early-phase trial units in Europe and, with Cancer Research UK, the Manchester Cancer Research Centre, with Corinne Faivre-Finn, Caroline Dive, Ananya Choudhury, Andrew Wardley and Juan W. Valle among its people. OnCo links it to bladder cancer, lymphoma and mesothelioma, and to ideas on core-funded radiotherapy trials, evening trial clinics for working-age patients and lung screening in supermarket car parks. Fragmented care and guideline gaps are the bottleneck it most often meets. Its proton and early-phase programmes are the place to start.","asOf":"2026-09-04","wikipedia":"https://en.wikipedia.org/wiki/The_Christie_NHS_Foundation_Trust","links":[{"label":"Official website","url":"https://www.christie.nhs.uk"},{"label":"PTCOG: particle therapy facilities in operation","url":"https://www.ptcog.site/index.php/facilities-in-operation-public"}],"tags":[],"related":[],"cancers":["tnbc","nsclc","lung-cancer","sclc"],"sections":[],"technologies":["proton-therapy","proton-therapy-systems","mr-linac","tomotherapy"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":["convert","violet"],"people":["ashya-king","corinne-faivre-finn","juan-valle","ananya-choudhury","andrew-wardley","caroline-dive","fiona-blackhall","rob-bristow","anne-armstrong","philip-crosbie"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Manchester","country":"GB","lat":53.43,"lng":-2.23,"institutionType":"cancer-center","website":"https://www.christie.nhs.uk","newsweekOncology2026":23,"university":"University of Manchester","programs":["Proton therapy","Early-phase trials","Radiotherapy research"]},"route":"/institutions/the-christie/","neighbours":{"cancer":[{"id":"urothelial","kind":"cancer","name":"Bladder & urothelial cancer","route":"/cancers/urothelial/"},{"id":"dlbcl","kind":"cancer","name":"Diffuse large B-cell lymphoma","route":"/cancers/dlbcl/"},{"id":"lung-cancer","kind":"cancer","name":"Lung cancer (all types)","route":"/cancers/lung-cancer/"},{"id":"mesothelioma","kind":"cancer","name":"Mesothelioma","route":"/cancers/mesothelioma/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"technology":[{"id":"mr-linac","kind":"technology","name":"MR-guided adaptive radiotherapy","route":"/technologies/mr-linac/"},{"id":"proton-therapy","kind":"technology","name":"Proton therapy","route":"/technologies/proton-therapy/"},{"id":"proton-therapy-systems","kind":"technology","name":"Proton therapy machines: cyclotrons, synchrotrons and single-room systems","route":"/technologies/proton-therapy-systems/"},{"id":"tomotherapy","kind":"technology","name":"TomoTherapy and Radixact (helical radiotherapy)","route":"/technologies/tomotherapy/"}],"trial":[{"id":"abc-12","kind":"trial","name":"ABC-12","route":"/trials/abc-12/"},{"id":"convert","kind":"trial","name":"CONVERT","route":"/trials/convert/"},{"id":"determine-trial","kind":"trial","name":"DETERMINE","route":"/trials/determine-trial/"},{"id":"precision-panc","kind":"trial","name":"Precision-Panc","route":"/trials/precision-panc/"},{"id":"target-national","kind":"trial","name":"TARGET National","route":"/trials/target-national/"},{"id":"violet","kind":"trial","name":"VIOLET","route":"/trials/violet/"}],"person":[{"id":"ananya-choudhury","kind":"person","name":"Ananya Choudhury","route":"/people/ananya-choudhury/"},{"id":"andrew-wardley","kind":"person","name":"Andrew Wardley","route":"/people/andrew-wardley/"},{"id":"anne-armstrong","kind":"person","name":"Anne Armstrong","route":"/people/anne-armstrong/"},{"id":"ashya-king","kind":"person","name":"Ashya King","route":"/people/ashya-king/"},{"id":"caroline-dive","kind":"person","name":"Caroline Dive","route":"/people/caroline-dive/"},{"id":"corinne-faivre-finn","kind":"person","name":"Corinne Faivre-Finn","route":"/people/corinne-faivre-finn/"},{"id":"fiona-blackhall","kind":"person","name":"Fiona Blackhall","route":"/people/fiona-blackhall/"},{"id":"juan-valle","kind":"person","name":"Juan W. Valle","route":"/people/juan-valle/"},{"id":"mairead-mcnamara","kind":"person","name":"Mairéad McNamara","route":"/people/mairead-mcnamara/"},{"id":"philip-crosbie","kind":"person","name":"Philip Crosbie","route":"/people/philip-crosbie/"},{"id":"rob-bristow","kind":"person","name":"Rob Bristow","route":"/people/rob-bristow/"}],"institution":[{"id":"ammf","kind":"institution","name":"AMMF, the Cholangiocarcinoma Charity","route":"/institutions/ammf/"},{"id":"cruk-manchester-institute","kind":"institution","name":"Cancer Research UK Manchester Institute","route":"/institutions/cruk-manchester-institute/"},{"id":"greater-manchester-cancer-alliance","kind":"institution","name":"Greater Manchester Cancer Alliance","route":"/institutions/greater-manchester-cancer-alliance/"},{"id":"manchester-royal-infirmary","kind":"institution","name":"Manchester Royal Infirmary HPB Unit","route":"/institutions/manchester-royal-infirmary/"}],"paper":[{"id":"paper-abc-06-folfox-second-line-lancet-oncol-2021","kind":"paper","name":"Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial","route":"/key-papers/paper-abc-06-folfox-second-line-lancet-oncol-2021/"}],"roadmap":[{"id":"gallbladder-cancer-roadmap","kind":"roadmap","name":"Gallbladder cancer roadmap: from a chance finding at gallstone surgery to a disease with its own trials","route":"/roadmaps/gallbladder-cancer-roadmap/"},{"id":"radiation-roadmap","kind":"roadmap","name":"Radiotherapy roadmap: X-rays → shaped beams → fewer fractions, particles and FLASH","route":"/roadmaps/radiation-roadmap/"}],"bottleneck":[{"id":"b-care-fragmentation","kind":"bottleneck","name":"Fragmented care and guideline gaps","route":"/bottlenecks/b-care-fragmentation/"}],"idea":[{"id":"idea-fund-non-drug-trial-quota","kind":"idea","name":"A statutory minimum share of public trial money for surgery and radiotherapy","route":"/ideas/idea-fund-non-drug-trial-quota/"},{"id":"idea-fund-radiotherapy-trials-infrastructure","kind":"idea","name":"Core-funded radiotherapy trials infrastructure with central quality assurance","route":"/ideas/idea-fund-radiotherapy-trials-infrastructure/"},{"id":"idea-tr1-evening-weekend-trial-clinics","kind":"idea","name":"Evening and weekend trial clinics for working-age patients","route":"/ideas/idea-tr1-evening-weekend-trial-clinics/"},{"id":"idea-prev-mobile-lung-screening-deprived-areas","kind":"idea","name":"Take lung screening scanners to supermarket car parks in the poorest areas","route":"/ideas/idea-prev-mobile-lung-screening-deprived-areas/"}]}}