{"entity":{"id":"tai-shan6","kind":"trial","name":"A Study of DZD8586 Versus Investigator's Choice in r/r CLL/SLL (TAI-SHAN6)","aka":["TAI-SHAN6"],"tldr":"A phase 3 trial testing DZD8586 in chronic lymphocytic leukaemia, now recruiting.","summary":"A Study of DZD8586 Versus Investigator's Choice in r/r CLL/SLL (TAI-SHAN6) is a phase 3 interventional study registered as NCT07139873, led by Dizal Pharmaceuticals, and recruiting on the registry. Official title: A Phase 3, Open-Label, Randomised, Multicenter Study to Evaluate Anti-tumour Efficacy of DZD8586 Versus Investigator's Choice in Patients With Relapsed/Refractory Chronic Lymphocytic Leukaemia/Small Lymphocytic Lymphoma. Planned enrolment is 250 participants (estimated). The study started in 2025-09-08 and primary completion is expected in 2029-01. No results have been posted on ClinicalTrials.gov.","status":"recruiting","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT07139873","url":"https://clinicaltrials.gov/study/NCT07139873"}],"tags":["ctgov-ingest"],"related":[],"cancers":["cll","cll-relapsed"],"sections":[],"technologies":[],"targets":[],"drugs":["dzd8586"],"companies":["dizal"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07139873","phase":"3","setting":"A Phase 3, Open-Label, Randomized, Multicenter Study to Evaluate Anti-tumor Efficacy of DZD8586 Versus Investigator's Choice in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma","sponsor":"Dizal Pharmaceuticals","started":"2025-09-08","startedType":"actual","enrolled":250,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/tai-shan6/","neighbours":{"cancer":[{"id":"cll","kind":"cancer","name":"Chronic lymphocytic leukaemia","route":"/cancers/cll/"},{"id":"cll-relapsed","kind":"cancer","name":"Relapsed or refractory chronic lymphocytic leukaemia","route":"/cancers/cll-relapsed/"}],"drug":[{"id":"dzd8586","kind":"drug","name":"DZD8586","route":"/drugs/dzd8586/"}],"company":[{"id":"dizal","kind":"company","name":"Dizal Pharmaceutical","route":"/companies/dizal/"}]}}