{"entity":{"id":"su-weiguo","kind":"person","name":"Weiguo Su","aka":["苏慰国"],"tldr":"Weiguo Su led the Shanghai chemistry that produced fruquintinib, savolitinib and surufatinib, three Chinese-discovered cancer pills approved at home and, for fruquintinib, in the US.","summary":"A former Pfizer chemist who joined Hutchmed in 2005 as head of research and became CEO in 2022; his team designed fruquintinib (FDA approval 2023 via Takeda), the selective MET inhibitor savolitinib (partnered with AstraZeneca) and surufatinib, the first Chinese-discovered small molecules to reach global markets.","asOf":"2026-09-10","links":[{"label":"Hutchmed","url":"https://www.hutch-med.com/"}],"tags":["china"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":["fruquintinib","savolitinib"],"companies":["hutchmed"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"CEO and Chief Scientific Officer, Hutchmed","specialisms":["Kinase inhibitor discovery","Medicinal chemistry"],"profiles":[{"label":"Hutchmed","url":"https://www.hutch-med.com/"}],"papers":[{"title":"Effect of Fruquintinib vs Placebo on Overall Survival in Patients With Previously Treated Metastatic Colorectal Cancer","journal":"JAMA","year":2018,"doi":"10.1001/jama.2018.7855"},{"title":"Once-daily savolitinib in Chinese patients with pulmonary sarcomatoid carcinomas and other non-small-cell lung cancers harbouring MET exon 14 skipping alterations: a multicentre, single-arm, open-label, phase 2 study","journal":"The Lancet Respiratory Medicine","year":2021,"doi":"10.1016/s2213-2600(21)00084-9"},{"title":"Surufatinib in advanced extrapancreatic neuroendocrine tumours (SANET-ep): a randomised, double-blind, placebo-controlled, phase 3 study","journal":"The Lancet Oncology","year":2020,"doi":"10.1016/s1470-2045(20)30496-4"}]},"route":"/people/su-weiguo/","neighbours":{"drug":[{"id":"fruquintinib","kind":"drug","name":"Fruquintinib","route":"/drugs/fruquintinib/"},{"id":"savolitinib","kind":"drug","name":"Savolitinib","route":"/drugs/savolitinib/"}],"company":[{"id":"hutchmed","kind":"company","name":"Hutchmed","route":"/companies/hutchmed/"}]}}