{"entity":{"id":"stefan-froehling","kind":"person","name":"Stefan Fröhling","aka":[],"tldr":"Runs the NCT/DKTK MASTER programme that sequences whole genomes of rare and young-adult cancers to guide therapy.","summary":"Stefan Fröhling is Managing Director of NCT Heidelberg and Head of Translational Medical Oncology at the German Cancer Research Center (DKFZ). His specialisms are precision oncology, sarcoma and genomics-guided trials, using whole-exome and whole-genome sequencing and comprehensive genomic profiling. He runs the NCT/DKTK MASTER programme, which sequences the whole genomes of rare and young-adult cancers to guide therapy. His Cancer Discovery paper on MASTER described comprehensive genomic and transcriptomic analysis for guiding therapeutic decisions in patients with rare cancers. His focus is on sarcomas and rare cancers and on turning genomic findings into molecularly guided treatment. His publications are listed on PubMed.","asOf":"2026-09-08","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Frohling%20S%5BAuthor%5D%20MASTER%20precision%20oncology"}],"tags":[],"related":[],"cancers":["sarcoma"],"sections":[],"technologies":["wes-wgs","cgp"],"targets":[],"drugs":[],"companies":[],"institutions":["heidelberg-nct","dkfz"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Managing Director, NCT Heidelberg; Head of Translational Medical Oncology, DKFZ","institutionId":"heidelberg-nct","specialisms":["Precision oncology","Sarcoma","Genomics-guided trials"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Frohling%20S%5BAuthor%5D%20MASTER%20precision%20oncology"}],"papers":[{"title":"Comprehensive genomic and transcriptomic analysis for guiding therapeutic decisions in patients with rare cancers (MASTER)","journal":"Cancer Discovery","year":2021,"doi":"10.1158/2159-8290.CD-21-0126"}]},"route":"/people/stefan-froehling/","neighbours":{"cancer":[{"id":"sarcoma","kind":"cancer","name":"Sarcomas (soft tissue, bone, GIST)","route":"/cancers/sarcoma/"}],"technology":[{"id":"cgp","kind":"technology","name":"Comprehensive genomic profiling","route":"/technologies/cgp/"},{"id":"wes-wgs","kind":"technology","name":"Whole-exome & whole-genome sequencing","route":"/technologies/wes-wgs/"}],"institution":[{"id":"dnpm","kind":"institution","name":"Deutsches Netzwerk für Personalisierte Medizin","route":"/institutions/dnpm/"},{"id":"dktk","kind":"institution","name":"German Cancer Consortium (DKTK)","route":"/institutions/dktk/"},{"id":"dkfz","kind":"institution","name":"German Cancer Research Center (DKFZ)","route":"/institutions/dkfz/"},{"id":"heidelberg-nct","kind":"institution","name":"Heidelberg University Hospital / NCT / DKFZ","route":"/institutions/heidelberg-nct/"}]}}