{"entity":{"id":"stefan-bielack","kind":"person","name":"Stefan S. Bielack","aka":[],"tldr":"Leads the COSS group and co-led EURAMOS-1, the largest osteosarcoma trial ever run.","summary":"Stefan Bielack (Stuttgart) chairs the Cooperative Osteosarcoma Study Group and was a lead investigator of EURAMOS-1, the 2,260-patient international trial showing that neither adding ifosfamide-etoposide for poor responders nor interferon for good responders improves outcomes over MAP chemotherapy, fixing MAP as the global standard. His COSS registry analyses define prognostic factors in osteosarcoma.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Bielack%20SS%5BAuthor%5D%20osteosarcoma"}],"tags":["paediatric","osteosarcoma","cooperative-group"],"related":[],"cancers":["osteosarcoma"],"sections":[],"technologies":["cytotoxic-chemotherapy"],"targets":[],"drugs":[],"companies":[],"institutions":["klinikum-stuttgart-olgahospital"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Head of Paediatric Oncology, Klinikum Stuttgart Olgahospital; Chair, Cooperative Osteosarcoma Study Group","institutionId":"klinikum-stuttgart-olgahospital","specialisms":["Osteosarcoma","Paediatric oncology","Bone tumours","International trials"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Bielack%20SS%5BAuthor%5D%20osteosarcoma"}],"papers":[{"title":"Methotrexate, doxorubicin, and cisplatin (MAP) plus maintenance pegylated interferon alfa-2b versus MAP alone in patients with resectable high-grade osteosarcoma and good histologic response to preoperative MAP (EURAMOS-1)","journal":"JCO","year":2015,"doi":"10.1200/JCO.2014.60.0734"},{"title":"Prognostic factors in high-grade osteosarcoma of the extremities or trunk: an analysis of 1,702 patients treated on neoadjuvant cooperative osteosarcoma study group protocols","journal":"JCO","year":2002,"doi":"10.1200/JCO.2002.20.3.776"}]},"route":"/people/stefan-bielack/","neighbours":{"cancer":[{"id":"osteosarcoma","kind":"cancer","name":"Osteosarcoma","route":"/cancers/osteosarcoma/"}],"technology":[{"id":"cytotoxic-chemotherapy","kind":"technology","name":"Cytotoxic chemotherapy","route":"/technologies/cytotoxic-chemotherapy/"}],"institution":[{"id":"klinikum-stuttgart-olgahospital","kind":"institution","name":"Klinikum Stuttgart / Olgahospital","route":"/institutions/klinikum-stuttgart-olgahospital/"}]}}