{"entity":{"id":"sr-one","kind":"company","name":"SR One","aka":[],"tldr":"SR One is a transatlantic biotech venture firm that began as GSK's corporate venture arm and now invests independently from London and the US West Coast. Oncology accounts for a large share of its portfolio, including Akamis Bio (gene-based immunotherapy), Avenzo Therapeutics, Charm Therapeutics (menin inhibitors for acute myeloid leukaemia) and Biotheryx (protein degradation).","summary":"SR One describes itself as 'a biotechnology venture capital firm, partnering with founders and entrepreneurs to translate innovative science into medicines', taking a 'back-and-build approach' to companies with strong fundamentals and a clearly defined development pathway. Its investing team 'is situated in key biotechnology hubs on the West Coast, USA and London, UK'; the operating entity is SR One Capital Management. Oncology is one of its portfolio filters and accounts for a large share of the companies listed: Akamis Bio (gene-based immuno-oncology for solid tumours), Ancora Biotech (biologics for oncology and inflammation), Avenzo Therapeutics (best-in-class oncology pipeline), Biotheryx (targeted protein degradation), Charm Therapeutics (menin inhibitors for acute myeloid leukaemia), Dren Bio, Effector, Fore Biotherapeutics, Simcha Therapeutics (IL-18) and Telios Pharma (blood cancers).","asOf":"2026-09-10","links":[{"label":"Official website","url":"https://www.srone.com/"},{"label":"Portfolio","url":"https://www.srone.com/portfolio"}],"tags":["vc"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":["gsk","avenzo"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":["The task hint gave Philadelphia and London; the site lists West Coast USA and London, so London is used. Founding year and the GSK spin-out are not stated on fetched pages. Avenzo is already in the graph."],"hq":"London","country":"GB","companyType":"investor","website":"https://www.srone.com/","investors":[],"funding":[]},"route":"/companies/sr-one/","neighbours":{"company":[{"id":"avenzo","kind":"company","name":"Avenzo Therapeutics","route":"/companies/avenzo/"},{"id":"gsk","kind":"company","name":"GSK","route":"/companies/gsk/"},{"id":"nimbus-therapeutics","kind":"company","name":"Nimbus Therapeutics","route":"/companies/nimbus-therapeutics/"}]}}