{"entity":{"id":"shari-pilon-thomas","kind":"person","name":"Shari Pilon-Thomas","aka":[],"tldr":"Shari Pilon-Thomas is the immunologist behind Moffitt's TIL manufacturing and the biology of who responds.","summary":"Shari Pilon-Thomas is a Senior Member in Immunology and Scientific Director of Cellular Therapy at Moffitt Cancer Center. She is the immunologist behind Moffitt's tumour-infiltrating lymphocyte manufacturing and the biology of who responds to it, leading translational immunology for the centre's TIL and cell therapy programmes. Her selected paper shows that neutralising tumour acidity improves anti-tumour responses to immunotherapy. She continues to study tumour acidity and resistance to immunotherapy in melanoma.","asOf":"2026-09-08","links":[{"label":"Moffitt profile","url":"https://www.moffitt.org/research-science/researchers/shari-pilon-thomas/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Pilon-Thomas%20S%5BAuthor%5D"}],"tags":[],"related":[],"cancers":["melanoma"],"sections":[],"technologies":["til-therapy"],"targets":[],"drugs":[],"companies":[],"institutions":["moffitt"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["cancer-research"],"dependsOn":[],"notes":[],"role":"Senior Member, Immunology; Scientific Director, Cellular Therapy","institutionId":"moffitt","specialisms":["TIL therapy","Tumour immunology","Immunotherapy resistance"],"profiles":[{"label":"Moffitt profile","url":"https://www.moffitt.org/research-science/researchers/shari-pilon-thomas/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Pilon-Thomas%20S%5BAuthor%5D"}],"papers":[{"title":"Neutralization of tumor acidity improves antitumor responses to immunotherapy","journal":"Cancer Research","year":2016,"url":"https://doi.org/10.1158/0008-5472.CAN-15-1743","doi":"10.1158/0008-5472.CAN-15-1743"}]},"route":"/people/shari-pilon-thomas/","neighbours":{"cancer":[{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"}],"technology":[{"id":"til-therapy","kind":"technology","name":"TIL therapy","route":"/technologies/til-therapy/"}],"institution":[{"id":"moffitt","kind":"institution","name":"Moffitt Cancer Center","route":"/institutions/moffitt/"}],"journal":[{"id":"cancer-research","kind":"journal","name":"Cancer Research","route":"/journals/cancer-research/"}]}}