{"entity":{"id":"shaare-zedek","kind":"institution","name":"Shaare Zedek Medical Center","aka":["Sha'are Zedek","Shaarei Tzedek"],"tldr":"Jerusalem's community-facing academic hospital, home of ESMO-MCBS architect Nathan Cherny and leading BRCA population screening research.","summary":"Founded in 1902, Shaare Zedek Medical Center is one of Jerusalem's two large academic hospitals. Nathan Cherny, who directs its cancer pain and palliative medicine service, chairs the working group behind the ESMO Magnitude of Clinical Benefit Scale used to grade the value of cancer treatments, and Ephrat Levy-Lahad's Medical Genetics Institute has led studies showing the feasibility of population-based BRCA1/2 screening in Ashkenazi Jewish women. The hospital's oncology and haematology institutes provide comprehensive treatment, and the centre has a strong tradition in supportive and palliative care, medical ethics and access to medicines research.","asOf":"2026-09-09","wikipedia":"https://en.wikipedia.org/wiki/Shaare_Zedek_Medical_Center","links":[{"label":"Homepage","url":"https://www.szmc.org.il/eng/"},{"label":"ESMO-MCBS","url":"https://www.esmo.org/guidelines/esmo-mcbs"}],"tags":[],"related":[],"cancers":["breast-hr-positive","ovarian","colorectal"],"sections":["supportive-care","prevention"],"technologies":["germline-testing","geriatric-assessment"],"targets":["brca"],"drugs":[],"companies":[],"institutions":["esmo","hadassah","hebrew-university-of-jerusalem"],"pathways":[],"terms":[],"trials":[],"people":["nathan-cherny","ofer-merin","ephrat-levy-lahad","rachel-michaelson-cohen","alberto-gabizon"],"bottlenecks":["b-palliative","b-hereditary-risk","b-drug-pricing"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Jerusalem","country":"IL","lat":31.774,"lng":35.198,"institutionType":"hospital","website":"https://www.szmc.org.il/eng/","university":"Hebrew University of Jerusalem","programs":["Palliative medicine and ESMO-MCBS","Medical genetics and BRCA population screening","Oncology and haematology institutes"]},"route":"/institutions/shaare-zedek/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"ovarian","kind":"cancer","name":"Ovarian cancer","route":"/cancers/ovarian/"}],"section":[{"id":"prevention","kind":"section","name":"Prevention & Risk","route":"/fronts/prevention/"},{"id":"supportive-care","kind":"section","name":"Supportive Care & Survivorship","route":"/fronts/supportive-care/"}],"technology":[{"id":"geriatric-assessment","kind":"technology","name":"Geriatric assessment","route":"/technologies/geriatric-assessment/"},{"id":"germline-testing","kind":"technology","name":"Germline (hereditary) testing","route":"/technologies/germline-testing/"}],"target":[{"id":"brca","kind":"target","name":"BRCA1 / BRCA2 (HRD)","route":"/targets/brca/"}],"institution":[{"id":"esmo","kind":"institution","name":"European Society for Medical Oncology (ESMO)","route":"/institutions/esmo/"},{"id":"hadassah","kind":"institution","name":"Hadassah Medical Center","route":"/institutions/hadassah/"},{"id":"hebrew-university-of-jerusalem","kind":"institution","name":"Hebrew University of Jerusalem","route":"/institutions/hebrew-university-of-jerusalem/"}],"person":[{"id":"alberto-gabizon","kind":"person","name":"Alberto Gabizon","route":"/people/alberto-gabizon/"},{"id":"ephrat-levy-lahad","kind":"person","name":"Ephrat Levy-Lahad","route":"/people/ephrat-levy-lahad/"},{"id":"nathan-cherny","kind":"person","name":"Nathan Cherny","route":"/people/nathan-cherny/"},{"id":"ofer-merin","kind":"person","name":"Ofer Merin","route":"/people/ofer-merin/"},{"id":"rachel-michaelson-cohen","kind":"person","name":"Rachel Michaelson-Cohen","route":"/people/rachel-michaelson-cohen/"}],"bottleneck":[{"id":"b-hereditary-risk","kind":"bottleneck","name":"Inherited risk is mostly unidentified","route":"/bottlenecks/b-hereditary-risk/"},{"id":"b-palliative","kind":"bottleneck","name":"Pain relief and palliative care are unavailable to most","route":"/bottlenecks/b-palliative/"},{"id":"b-drug-pricing","kind":"bottleneck","name":"Prices and value","route":"/bottlenecks/b-drug-pricing/"}],"paper":[{"id":"paper-gabai-kapara-population-brca-screening-pnas-2014","kind":"paper","name":"Population-based screening for breast and ovarian cancer risk due to BRCA1 and BRCA2","route":"/key-papers/paper-gabai-kapara-population-brca-screening-pnas-2014/"}]}}