{"entity":{"id":"sanford-burnham-prebys","kind":"institution","name":"Sanford Burnham Prebys Medical Discovery Institute","aka":["Sanford Burnham Prebys","La Jolla Cancer Research Foundation"],"tldr":"Sanford Burnham Prebys in La Jolla is an NCI basic laboratory cancer centre whose founding work on integrins and RGD adhesion peptides created the field of tumour-homing peptides; its Prebys Center for Chemical Genomics is one of the largest non-profit drug-screening facilities in academia.","summary":"Founded in 1976 by Erkki Ruoslahti as the La Jolla Cancer Research Foundation and NCI-designated since 1981, Sanford Burnham Prebys is a basic laboratory cancer centre whose founding discoveries in integrins and RGD adhesion peptides created the field of tumour-homing peptides. The Conrad Prebys Center for Chemical Genomics is one of the largest non-profit drug discovery and high-throughput screening facilities in academia. Current programmes span cancer metabolism, the tumour microenvironment and immune evasion, paediatric cancers and computational biology. The institute works alongside Salk, Scripps and UC San Diego on the Torrey Pines mesa.","asOf":"2026-09-09","wikipedia":"https://en.wikipedia.org/wiki/Sanford_Burnham_Prebys","links":[{"label":"Sanford Burnham Prebys","url":"https://sbpdiscovery.org"},{"label":"NCI-designated Cancer Center","url":"https://sbpdiscovery.org/research/cancer-center/"}],"tags":[],"related":[],"cancers":[],"sections":["drug-discovery"],"technologies":["peptide-drug-conjugate","functional-drug-testing"],"targets":[],"drugs":[],"companies":[],"institutions":["ucsd-moores"],"pathways":[],"terms":[],"trials":[],"people":["paul-boutros"],"bottlenecks":["b-undruggable-targets","b-tme-immunosuppression"],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"La Jolla, CA","country":"US","lat":32.896,"lng":-117.24,"institutionType":"research-institute","website":"https://sbpdiscovery.org","nci":"basic","programs":["Drug discovery (Prebys Center)","Cell adhesion and tumour microenvironment","Cancer metabolism"]},"route":"/institutions/sanford-burnham-prebys/","neighbours":{"section":[{"id":"drug-discovery","kind":"section","name":"Drug Discovery Platforms","route":"/fronts/drug-discovery/"}],"technology":[{"id":"functional-drug-testing","kind":"technology","name":"Functional (ex vivo) drug testing","route":"/technologies/functional-drug-testing/"},{"id":"peptide-drug-conjugate","kind":"technology","name":"Peptide-drug & small-molecule-drug conjugates","route":"/technologies/peptide-drug-conjugate/"}],"institution":[{"id":"nci","kind":"institution","name":"National Cancer Institute (NIH)","route":"/institutions/nci/"},{"id":"ucsd-moores","kind":"institution","name":"UC San Diego Moores Cancer Center","route":"/institutions/ucsd-moores/"}],"person":[{"id":"paul-boutros","kind":"person","name":"Paul Boutros","route":"/people/paul-boutros/"}],"bottleneck":[{"id":"b-tme-immunosuppression","kind":"bottleneck","name":"Cold tumours and the immunosuppressive microenvironment","route":"/bottlenecks/b-tme-immunosuppression/"},{"id":"b-undruggable-targets","kind":"bottleneck","name":"The undruggable drivers","route":"/bottlenecks/b-undruggable-targets/"}],"collection":[{"id":"nci-cancer-centers","kind":"collection","name":"NCI-Designated Cancer Centers","route":"/collections/nci-cancer-centers/"}]}}