{"entity":{"id":"san-raffaele","kind":"institution","name":"IRCCS Ospedale San Raffaele","aka":["San Raffaele Hospital","OSR","Università Vita-Salute San Raffaele"],"tldr":"Milan's research hospital known for engineered T-cell therapies, gene therapy, high-volume pancreatic surgery and HER2 breast cancer trials.","summary":"Ospedale San Raffaele is a private IRCCS research hospital with its own university and a strong gene and cell therapy tradition through the San Raffaele Telethon Institute for Gene Therapy. Fabio Ciceri's haematology and transplant unit and Chiara Bonini's experimental haematology laboratory developed suicide-gene-modified donor lymphocytes and TCR-edited T cells, Luca Gianni's breast oncology programme led the NeoSphere trial of dual HER2 blockade with pertuzumab and trastuzumab, and Massimo Falconi's pancreatic surgery unit is among Europe's highest-volume centres. The hospital runs neuro-oncology, urology, radiotherapy and a phase 1 unit, and pathology under Claudio Doglioni supports genomics-driven trials.","asOf":"2026-09-09","wikipedia":"https://en.wikipedia.org/wiki/San_Raffaele_Hospital","links":[{"label":"Homepage","url":"https://www.hsr.it"},{"label":"Research","url":"https://research.hsr.it"}],"tags":[],"related":[],"cancers":["all-leukemia","aml","pancreatic","breast-her2-positive","neuroendocrine"],"sections":["cell-therapy","surgery"],"technologies":["tcr-t","car-t","allogeneic-cell-therapy","robotic-surgery"],"targets":["her2"],"drugs":["trastuzumab"],"companies":[],"institutions":["ieo-milan","int-milan"],"pathways":[],"terms":[],"trials":[],"people":["gianvito-martino","andrea-necchi","andres-ferreri","marco-centenari"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Milan","country":"IT","lat":45.505,"lng":9.264,"institutionType":"hospital","website":"https://www.hsr.it","university":"Università Vita-Salute San Raffaele","programs":["Engineered T-cell and gene therapy","Haematology and transplantation","Pancreatic surgery","HER2-positive breast cancer trials","Neuro-oncology"]},"route":"/institutions/san-raffaele/","neighbours":{"cancer":[{"id":"all-leukemia","kind":"cancer","name":"Acute lymphoblastic leukaemia","route":"/cancers/all-leukemia/"},{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"},{"id":"breast-her2-positive","kind":"cancer","name":"HER2-positive breast cancer","route":"/cancers/breast-her2-positive/"},{"id":"neuroendocrine","kind":"cancer","name":"Neuroendocrine tumours","route":"/cancers/neuroendocrine/"},{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"section":[{"id":"cell-therapy","kind":"section","name":"Cell Therapy","route":"/fronts/cell-therapy/"},{"id":"surgery","kind":"section","name":"Surgery & Interventional","route":"/fronts/surgery/"}],"technology":[{"id":"allogeneic-cell-therapy","kind":"technology","name":"Allogeneic (off-the-shelf) cell therapy","route":"/technologies/allogeneic-cell-therapy/"},{"id":"car-t","kind":"technology","name":"CAR-T cell therapy","route":"/technologies/car-t/"},{"id":"robotic-surgery","kind":"technology","name":"Robotic & minimally invasive surgery","route":"/technologies/robotic-surgery/"},{"id":"tcr-t","kind":"technology","name":"TCR-T cell therapy","route":"/technologies/tcr-t/"}],"target":[{"id":"her2","kind":"target","name":"HER2","route":"/targets/her2/"}],"drug":[{"id":"trastuzumab","kind":"drug","name":"Trastuzumab","route":"/drugs/trastuzumab/"}],"institution":[{"id":"int-milan","kind":"institution","name":"Fondazione IRCCS Istituto Nazionale dei Tumori","route":"/institutions/int-milan/"},{"id":"ieo-milan","kind":"institution","name":"IEO (European Institute of Oncology)","route":"/institutions/ieo-milan/"}],"person":[{"id":"andrea-necchi","kind":"person","name":"Andrea Necchi","route":"/people/andrea-necchi/"},{"id":"andres-ferreri","kind":"person","name":"Andrés J. M. Ferreri","route":"/people/andres-ferreri/"},{"id":"gianvito-martino","kind":"person","name":"Gianvito Martino","route":"/people/gianvito-martino/"},{"id":"marco-centenari","kind":"person","name":"Marco Centenari","route":"/people/marco-centenari/"}]}}