{"entity":{"id":"ramaswamy-govindan","kind":"person","name":"Ramaswamy Govindan","aka":[],"tldr":"Showed how smoking-related lung cancers carry ten times the mutations of never-smokers' tumours.","summary":"Ramaswamy Govindan holds the Anheuser-Busch Chair in Medical Oncology and is Director of the Section of Medical Oncology at Siteman Cancer Center, Washington University. He is a thoracic oncologist known for leading the genomic characterisation of lung cancer in smokers and never-smokers, showing that smoking-related tumours carry ten times the mutations of never-smokers' tumours. His selected paper reports the genomic landscape of non-small-cell lung cancer in smokers and never-smokers. He has led multiple cooperative-group lung trials and continues to work on immunotherapy in lung cancer.","asOf":"2026-09-08","links":[{"label":"WashU profile","url":"https://oncology.wustl.edu/people/ramaswamy-govindan-md/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Govindan%20R%5BAuthor%5D"}],"tags":[],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["wustl-siteman"],"pathways":[],"terms":["tmb"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Anheuser-Busch Chair in Medical Oncology; Director, Section of Medical Oncology","institutionId":"wustl-siteman","specialisms":["Lung cancer","Genomics of smokers' lung cancer","Immunotherapy"],"profiles":[{"label":"WashU profile","url":"https://oncology.wustl.edu/people/ramaswamy-govindan-md/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Govindan%20R%5BAuthor%5D"}],"papers":[{"title":"Genomic landscape of non-small cell lung cancer in smokers and never-smokers","journal":"Cell","year":2012,"url":"https://doi.org/10.1016/j.cell.2012.08.024","doi":"10.1016/j.cell.2012.08.024"}]},"route":"/people/ramaswamy-govindan/","neighbours":{"cancer":[{"id":"kras-g12c-nsclc","kind":"cancer","name":"KRAS G12C-mutant non-small-cell lung cancer","route":"/cancers/kras-g12c-nsclc/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"institution":[{"id":"wustl-siteman","kind":"institution","name":"Siteman Cancer Center, Washington University","route":"/institutions/wustl-siteman/"}],"term":[{"id":"tmb","kind":"term","name":"Tumour mutational burden (TMB)","route":"/terms/tmb/"}]}}