{"entity":{"id":"ralph-weichselbaum","kind":"person","name":"Ralph Weichselbaum","aka":[],"tldr":"Radiation oncologist at the University of Chicago known for the oligometastasis concept and for research linking radiation with anti-tumour immunity.","summary":"Ralph Weichselbaum, MD, is a member of the Executive Committee of the University of Chicago Medicine Comprehensive Cancer Center and a long-standing leader of its radiation oncology programme. With Samuel Hellman he proposed the oligometastasis hypothesis, and his laboratory studies how radiation interacts with innate and adaptive immunity, including STING pathway signalling. His role is listed on the centre's leadership page.","asOf":"2026-09-10","wikipedia":"https://en.wikipedia.org/wiki/Ralph_Weichselbaum","links":[{"label":"Institution profile","url":"https://www.uchicagomedicine.org/cancer/about-us/leadership"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Weichselbaum+RR%5BAuthor%5D"}],"tags":["clinician-scientist","radiotherapy","immunotherapy"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["uchicago-cancer"],"pathways":[],"terms":["radiotherapy","immune-system"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Executive Committee Member","institutionId":"uchicago-cancer","specialisms":["Radiation oncology","Oligometastasis","Radiation and immunotherapy"],"profiles":[{"label":"Institution profile","url":"https://www.uchicagomedicine.org/cancer/about-us/leadership"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Weichselbaum+RR%5BAuthor%5D"}],"papers":[{"title":"Radiotherapy and immunotherapy: a beneficial liaison?","journal":"Nature Reviews Clinical Oncology","year":2017,"doi":"10.1038/nrclinonc.2016.211"},{"title":"STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors","journal":"Immunity","year":2014,"doi":"10.1016/j.immuni.2014.10.019"},{"title":"Oligometastases revisited","journal":"Nature Reviews Clinical Oncology","year":2011,"doi":"10.1038/nrclinonc.2011.44"}],"orcid":"0000-0002-5643-8939"},"route":"/people/ralph-weichselbaum/","neighbours":{"institution":[{"id":"uchicago-cancer","kind":"institution","name":"University of Chicago Medicine Comprehensive Cancer Center","route":"/institutions/uchicago-cancer/"}],"term":[{"id":"immune-system","kind":"term","name":"Immune system","route":"/terms/immune-system/"},{"id":"radiotherapy","kind":"term","name":"Radiotherapy","route":"/terms/radiotherapy/"}]}}