{"entity":{"id":"quynh-thu-le","kind":"person","name":"Quynh-Thu Le","aka":[],"tldr":"Chairs NRG Oncology, the largest US radiotherapy cooperative group, and leads head and neck de-escalation trials.","summary":"Quynh-Thu Le is group chair of NRG Oncology, which runs the national radiotherapy-based trials in the United States, and has led NRG head and neck studies including HN002 and HN005 on de-escalating radiotherapy for HPV-positive oropharyngeal cancer. Her laboratory studies tumour hypoxia and galectin-1 as targets and biomarkers, and she chairs radiation oncology at Stanford.","asOf":"2026-09-10","wikipedia":"https://en.wikipedia.org/wiki/Quynh-Thu_Le","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Le%20QT%5BAuthor%5D%20head%20neck%20radiotherapy%20hypoxia"}],"tags":["radiotherapy","head-and-neck","nrg-oncology"],"related":[],"cancers":["head-and-neck"],"sections":[],"technologies":["imrt-igrt"],"targets":[],"drugs":[],"companies":[],"institutions":["stanford"],"pathways":[],"terms":[],"trials":["nrg-hn002-hn005"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Chair of Radiation Oncology, Stanford University; Group Chair, NRG Oncology","institutionId":"stanford","specialisms":["Head and neck radiotherapy","Tumour hypoxia","Cooperative-group leadership","Biomarkers"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Le%20QT%5BAuthor%5D%20head%20neck%20radiotherapy%20hypoxia"}],"papers":[{"title":"Reduced-dose radiation therapy for HPV-associated oropharyngeal carcinoma (NRG Oncology HN002)","journal":"JCO","year":2021,"doi":"10.1200/JCO.20.03128"},{"title":"Galectin-1: a link between tumor hypoxia and tumor immune privilege","journal":"JCO","year":2005,"doi":"10.1200/jco.2005.02.0206"}],"orcid":"0000-0002-3682-1439"},"route":"/people/quynh-thu-le/","neighbours":{"cancer":[{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"}],"technology":[{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"institution":[{"id":"stanford","kind":"institution","name":"Stanford Health Care / Stanford Cancer Institute","route":"/institutions/stanford/"}],"trial":[{"id":"nrg-hn002-hn005","kind":"trial","name":"NRG-HN002 & NRG-HN005 (HPV+ de-escalation)","route":"/trials/nrg-hn002-hn005/"}]}}