{"entity":{"id":"pedro-ramirez","kind":"person","name":"Pedro T. Ramirez","aka":[],"tldr":"Surgeon who led the LACC trial, which unexpectedly showed keyhole hysterectomy worsens survival in early cervical cancer.","summary":"Pedro Ramirez (Houston Methodist; formerly MD Anderson) was principal investigator of LACC, the randomised trial showing minimally invasive radical hysterectomy leads to more recurrences and deaths than open surgery in early-stage cervical cancer, a result that reversed a decade of surgical practice. He has since led work on the mechanisms of this finding and on surgical technique modifications.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Ramirez%20PT%5BAuthor%5D%20cervical%20LACC"}],"tags":["cervical","surgery"],"related":[],"cancers":["cervical"],"sections":[],"technologies":["robotic-surgery"],"targets":[],"drugs":[],"companies":[],"institutions":["houston-methodist-neal-cancer-center"],"pathways":[],"terms":[],"trials":["lacc"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Chair, Department of Obstetrics and Gynecology, Houston Methodist Hospital","institutionId":"houston-methodist-neal-cancer-center","specialisms":["Gynaecologic oncology surgery","Minimally invasive surgery","Radical hysterectomy","Surgical trials"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Ramirez%20PT%5BAuthor%5D%20cervical%20LACC"}],"papers":[{"title":"Minimally invasive versus abdominal radical hysterectomy for cervical cancer (LACC)","journal":"NEJM","year":2018,"doi":"10.1056/NEJMoa1806395"},{"title":"Open vs minimally invasive radical hysterectomy in early cervical cancer: LACC trial final analysis","journal":"JCO","year":2024}]},"route":"/people/pedro-ramirez/","neighbours":{"cancer":[{"id":"cervical","kind":"cancer","name":"Cervical cancer","route":"/cancers/cervical/"}],"technology":[{"id":"robotic-surgery","kind":"technology","name":"Robotic & minimally invasive surgery","route":"/technologies/robotic-surgery/"}],"institution":[{"id":"houston-methodist-neal-cancer-center","kind":"institution","name":"Houston Methodist Dr. Mary and Ron Neal Cancer Center","route":"/institutions/houston-methodist-neal-cancer-center/"}],"trial":[{"id":"lacc","kind":"trial","name":"LACC (Laparoscopic Approach to Cervical Cancer)","route":"/trials/lacc/"}]}}