{"entity":{"id":"paper-torre-global-cancer-statistics-2012-cacancer-2015","kind":"paper","name":"Torre 2015: Global cancer statistics, 2012","aka":[],"tldr":"The GLOBOCAN-based world count for 2012: about 14.1 million new cancer cases, with more than half of cases and almost two thirds of deaths occurring in less developed regions, and lung cancer leading in men while breast cancer led in women.","summary":"Torre, Bray, Siegel and colleagues summarised the GLOBOCAN 2012 estimates for the American Cancer Society. They reported about 14.1 million new cases and 8.2 million deaths in 2012, with 57% of cases and 65% of deaths in less developed regions. Lung cancer was the leading cancer in men for both incidence and mortality; breast cancer led in women. The paper highlighted the rising share of the burden in transitioning countries and the potential of prevention, early detection and treatment to reduce it.","asOf":"2026-09-08","links":[{"label":"Full text (DOI)","url":"https://doi.org/10.3322/caac.21262"}],"tags":[],"related":["paper-bray-globocan-2018-cacancer-2018"],"cancers":["nsclc","breast-hr-positive"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["iarc"],"pathways":[],"terms":["incidence-vs-prevalence","mortality"],"trials":[],"people":["bray-freddie"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"journal":"CA: A Cancer Journal for Clinicians","year":2015,"doi":"10.3322/caac.21262","authors":"Torre LA, Bray F, Siegel RL, et al.","paperType":"observational","findings":["About 14.1 million new cancer cases and 8.2 million cancer deaths worldwide in 2012.","57% of cases and 65% of deaths occurred in less developed regions.","Lung cancer the leading cause of cancer incidence and death in men; breast cancer the leading cancer in women."],"whatItMeans":"One of the most cited descriptions of the global cancer burden of the 2010s, it framed the shift of cancer towards lower-income countries that later GLOBOCAN releases have confirmed.","caveats":["Superseded by the 2018, 2020 and 2022 GLOBOCAN releases.","Estimates for many countries were modelled from limited registry data."],"changedPractice":false},"route":"/key-papers/paper-torre-global-cancer-statistics-2012-cacancer-2015/","neighbours":{"paper":[{"id":"paper-bray-globocan-2018-cacancer-2018","kind":"paper","name":"Bray 2018: GLOBOCAN 2018, worldwide incidence and mortality for 36 cancers","route":"/key-papers/paper-bray-globocan-2018-cacancer-2018/"},{"id":"paper-ferlay-globocan-2012-methods-ijc-2015","kind":"paper","name":"Ferlay 2015: sources, methods and major patterns in GLOBOCAN 2012","route":"/key-papers/paper-ferlay-globocan-2012-methods-ijc-2015/"},{"id":"paper-jemal-global-cancer-statistics-2011-cacancer","kind":"paper","name":"Jemal 2011: Global cancer statistics (GLOBOCAN 2008)","route":"/key-papers/paper-jemal-global-cancer-statistics-2011-cacancer/"}],"cancer":[{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"institution":[{"id":"iarc","kind":"institution","name":"International Agency for Research on Cancer (IARC / WHO)","route":"/institutions/iarc/"}],"term":[{"id":"incidence-vs-prevalence","kind":"term","name":"Incidence versus prevalence","route":"/terms/incidence-vs-prevalence/"},{"id":"mortality","kind":"term","name":"Mortality","route":"/terms/mortality/"}],"person":[{"id":"bray-freddie","kind":"person","name":"Freddie Bray","route":"/people/bray-freddie/"}]}}