{"entity":{"id":"oncobox","kind":"company","name":"Oncobox","aka":[],"tldr":"Oncobox profiles a tumour's genes and the activity of its signalling pathways, then ranks approved targeted drugs by how likely they are to work for that patient.","summary":"Oncobox Dx combines tumour DNA and RNA sequencing with pathway-activation algorithms to score more than a hundred marketed targeted drugs for an individual patient with advanced cancer, returning a ranked report for the treating oncologist. Its YC profile cites a European and Asian study of about 900 late-stage patients in which the approach was associated with higher targeted-therapy effectiveness; that work is observational and the test has not been validated in a randomised trial. Oncobox remains active in the YC directory and markets to clinicians, hospitals and pharma.","asOf":"2026-09-10","links":[{"label":"Y Combinator profile","url":"https://www.ycombinator.com/companies/oncobox"},{"label":"Official website","url":"https://oncobox.com"}],"tags":["yc"],"related":[],"cancers":[],"sections":["diagnostics","targeted-therapy"],"technologies":["rna-seq","cgp"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Walnut, CA","country":"US","companyType":"diagnostics","website":"https://oncobox.com","stage":"startup","ycBatch":"S17","investors":["y-combinator"],"funding":[]},"route":"/companies/oncobox/","neighbours":{"section":[{"id":"diagnostics","kind":"section","name":"Diagnostics & Biomarkers","route":"/fronts/diagnostics/"},{"id":"targeted-therapy","kind":"section","name":"Targeted Therapy","route":"/fronts/targeted-therapy/"}],"technology":[{"id":"cgp","kind":"technology","name":"Comprehensive genomic profiling","route":"/technologies/cgp/"},{"id":"rna-seq","kind":"technology","name":"RNA sequencing & expression profiling","route":"/technologies/rna-seq/"}],"company":[{"id":"y-combinator","kind":"company","name":"Y Combinator","route":"/companies/y-combinator/"}]}}