{"entity":{"id":"obi-griffith","kind":"person","name":"Obi L. Griffith","aka":[],"tldr":"Obi Griffith co-leads CIViC and the open tooling that lets clinicians interpret tumour sequencing.","summary":"Obi L. Griffith is Associate Professor of Medicine and Assistant Director of the McDonnell Genome Institute at Siteman Cancer Center, Washington University. He is a computational biologist who co-leads CIViC, DoCM and pVACtools, the open tooling that lets clinicians interpret tumour sequencing, and the ClinGen somatic working group. His selected paper describes CIViC as a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer. He continues to work on clinical genomics, variant interpretation and open-source bioinformatics.","asOf":"2026-09-08","links":[{"label":"Griffith lab","url":"https://griffithlab.org"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Griffith%20OL%5BAuthor%5D"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":["cgp"],"targets":[],"drugs":[],"companies":[],"institutions":["wustl-siteman"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["nature-genetics"],"dependsOn":[],"notes":[],"role":"Associate Professor of Medicine; Assistant Director, McDonnell Genome Institute","institutionId":"wustl-siteman","specialisms":["Clinical genomics","Variant interpretation","Open-source bioinformatics"],"profiles":[{"label":"Griffith lab","url":"https://griffithlab.org"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Griffith%20OL%5BAuthor%5D"}],"papers":[{"title":"CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer","journal":"Nature Genetics","year":2017,"url":"https://doi.org/10.1038/ng.3774","doi":"10.1038/ng.3774"}],"orcid":"0000-0002-0843-4271"},"route":"/people/obi-griffith/","neighbours":{"technology":[{"id":"cgp","kind":"technology","name":"Comprehensive genomic profiling","route":"/technologies/cgp/"}],"institution":[{"id":"wustl-siteman","kind":"institution","name":"Siteman Cancer Center, Washington University","route":"/institutions/wustl-siteman/"}],"journal":[{"id":"nature-genetics","kind":"journal","name":"Nature Genetics","route":"/journals/nature-genetics/"}]}}