{"entity":{"id":"northstar-medical-radioisotopes","kind":"company","name":"NorthStar Medical Radioisotopes","aka":[],"tldr":"NorthStar is a non-reactor producer of Mo-99 in the US and an emerging supplier of non-carrier-added Lu-177 and Ac-225 made with electron accelerators.","summary":"NorthStar Medical Radioisotopes, based in Beloit, Wisconsin, is a non-reactor producer of molybdenum-99 in the United States and an emerging supplier of non-carrier-added lutetium-177 and actinium-225 made with electron accelerators. Its RadioGenix Mo-99 system was approved in 2018, its accelerator-based actinium-225 production facility came online in 2024 to 2025, and it holds lutetium-177 supply agreements. OnCo links it to the therapeutic isotope supply chain for Mo-99, Lu-177 and Ac-225. Whether accelerator production can supply actinium-225 at the volumes the alpha therapies in phase 3 will need is the open question. The isotope supply chain page carries the wider picture.","asOf":"2026-09-08","links":[{"label":"Official website","url":"https://www.northstarnm.com"}],"tags":["supporting"],"related":[],"cancers":[],"sections":["radiopharma"],"technologies":["therapy-isotope-supply-chain"],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"hq":"Beloit, WI","country":"US","companyType":"radiopharma","website":"https://www.northstarnm.com","investors":[],"funding":[]},"route":"/companies/northstar-medical-radioisotopes/","neighbours":{"section":[{"id":"radiopharma","kind":"section","name":"Radiopharmaceuticals & Theranostics","route":"/fronts/radiopharma/"}],"technology":[{"id":"actinium-225-supply","kind":"technology","name":"Actinium-225 supply: thorium stocks, accelerators and radium targets","route":"/technologies/actinium-225-supply/"},{"id":"research-reactor-isotope-production","kind":"technology","name":"Research reactors for medical isotopes (Mo-99, Lu-177, I-131)","route":"/technologies/research-reactor-isotope-production/"},{"id":"therapy-isotope-supply-chain","kind":"technology","name":"Therapeutic isotope supply chain (Mo-99, Lu-177, Ac-225)","route":"/technologies/therapy-isotope-supply-chain/"}]}}