{"entity":{"id":"nikolaus-rajewsky","kind":"person","name":"Nikolaus Rajewsky","aka":[],"tldr":"Systems biologist at the MDC known for microRNA and circular RNA discoveries and for single-cell and spatial genomics applied to cancer.","summary":"Nikolaus Rajewsky leads the Systems Biology of Gene Regulatory Elements laboratory at the Max Delbrück Center and heads its Berlin Institute for Medical Systems Biology (BIMSB). His group combines computational and experimental approaches to study non-coding RNAs, organoids and spatial transcriptomics, with disease programmes in triple-negative breast cancer, non-small cell lung cancer and neuroblastoma in collaboration with Charité.","asOf":"2026-09-10","links":[{"label":"Institution profile","url":"https://www.mdc-berlin.de/n-rajewsky"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Rajewsky+N%5BAuthor%5D"}],"tags":["clinician-scientist","systems biology","genomics","breast cancer"],"related":[],"cancers":["tnbc","nsclc","neuroblastoma"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["mdc-berlin"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Group Leader, Systems Biology of Gene Regulatory Elements; Scientific Director, Berlin Institute for Medical Systems Biology (MDC-BIMSB)","institutionId":"mdc-berlin","specialisms":["Systems biology","Single-cell and spatial transcriptomics","Non-coding RNA","Triple-negative breast cancer"],"profiles":[{"label":"Institution profile","url":"https://www.mdc-berlin.de/n-rajewsky"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Rajewsky+N%5BAuthor%5D"}],"papers":[{"title":"The oncogenic role of circPVT1 in head and neck squamous cell carcinoma is mediated through the mutant p53/YAP/TEAD transcription-competent complex","journal":"Genome Biology","year":2017,"doi":"10.1186/s13059-017-1368-y"}],"orcid":"0000-0002-4785-4332"},"route":"/people/nikolaus-rajewsky/","neighbours":{"cancer":[{"id":"neuroblastoma","kind":"cancer","name":"Neuroblastoma (paediatric)","route":"/cancers/neuroblastoma/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"tnbc","kind":"cancer","name":"Triple-negative breast cancer (TNBC)","route":"/cancers/tnbc/"}],"institution":[{"id":"mdc-berlin","kind":"institution","name":"Max Delbrück Center for Molecular Medicine","route":"/institutions/mdc-berlin/"}]}}