{"entity":{"id":"nct07516093","kind":"trial","name":"Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL","aka":[],"tldr":"A phase 3 trial testing Bexobrutideg in chronic lymphocytic leukaemia, now recruiting.","summary":"Study of NX-5948 Versus Pirtobrutinib in R/R CLL/SLL is a phase 3 interventional study registered as NCT07516093, led by Nurix Therapeutics, and recruiting on the registry. Official title: A Phase 3, Randomised, Open-label, Multicenter Study of NX-5948 Versus Pirtobrutinib in Relapsed/Refractory (R/R) Chronic Lymphocytic Leukaemia (CLL)/Small Lymphocytic Lymphoma (SLL). Planned enrolment is 620 participants (estimated). The study started in 2026-08-03 and primary completion is expected in 2029-10. No results have been posted on ClinicalTrials.gov.","status":"recruiting","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT07516093","url":"https://clinicaltrials.gov/study/NCT07516093"}],"tags":["ctgov-ingest"],"related":[],"cancers":["cll","cll-relapsed"],"sections":[],"technologies":[],"targets":[],"drugs":["bexobrutideg"],"companies":["nurix"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT07516093","phase":"3","setting":"A Phase 3, Randomized, Open-label, Multicenter Study of NX-5948 Versus Pirtobrutinib in Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)","sponsor":"Nurix Therapeutics","started":"2026-08-03","startedType":"actual","enrolled":620,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct07516093/","neighbours":{"cancer":[{"id":"cll","kind":"cancer","name":"Chronic lymphocytic leukaemia","route":"/cancers/cll/"},{"id":"cll-relapsed","kind":"cancer","name":"Relapsed or refractory chronic lymphocytic leukaemia","route":"/cancers/cll-relapsed/"}],"drug":[{"id":"bexobrutideg","kind":"drug","name":"Bexobrutideg","route":"/drugs/bexobrutideg/"}],"company":[{"id":"nurix","kind":"company","name":"Nurix Therapeutics","route":"/companies/nurix/"}]}}