{"entity":{"id":"nct06686576","kind":"trial","name":"A Study of Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer","aka":[],"tldr":"A phase 3 trial testing QL1706 in colorectal cancer, now recruiting.","summary":"A Study of Neoadjuvant QL1706 in Participants With Untreated dMMR/MSI-H Resectable Colon Cancer is a phase 3 interventional study registered as NCT06686576, led by Qilu Pharmaceutical, and recruiting on the registry. Official title: A Phase Ib/III, Open-Label, Randomised Study of Neoadjuvant QL1706 Versus Standard of Care in Participants With Untreated of Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer. Planned enrolment is 363 participants (estimated). The study started in 2024-12-12 and primary completion is expected in 2030-12. No results have been posted on ClinicalTrials.gov.","status":"recruiting","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT06686576","url":"https://clinicaltrials.gov/study/NCT06686576"}],"tags":["ctgov-ingest"],"related":[],"cancers":["colorectal","msi-high-colorectal"],"sections":[],"technologies":[],"targets":[],"drugs":["ql1706"],"companies":["qilu-pharmaceutical"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06686576","phase":"3","setting":"A Phase Ib/III, Open-Label, Randomized Study of Neoadjuvant QL1706 Versus Standard of Care in Participants With Untreated of Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer","sponsor":"Qilu Pharmaceutical","started":"2024-12-12","startedType":"actual","enrolled":363,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06686576/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"msi-high-colorectal","kind":"cancer","name":"Mismatch-repair deficient (MSI-high) colorectal cancer","route":"/cancers/msi-high-colorectal/"}],"drug":[{"id":"ql1706","kind":"drug","name":"QL1706","route":"/drugs/ql1706/"}],"company":[{"id":"qilu-pharmaceutical","kind":"company","name":"Qilu Pharmaceutical","route":"/companies/qilu-pharmaceutical/"}]}}