{"entity":{"id":"nct06616532","kind":"trial","name":"PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer","aka":[],"tldr":"A phase 3 trial testing PM8002 in small-cell lung cancer and non-small-cell lung cancer, active and no longer recruiting.","summary":"PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer is a phase 3 interventional study registered as NCT06616532, led by Biotheus, and active but no longer recruiting on the registry. Official title: A Multicenter, Open-lable, Randomised Phase III Study of PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer. Planned enrolment is 404 participants (estimated). The study started in 2024-11-13 and primary completion is expected in 2027-01-25. No results have been posted on ClinicalTrials.gov.","status":"active","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT06616532","url":"https://clinicaltrials.gov/study/NCT06616532"}],"tags":["ctgov-ingest"],"related":[],"cancers":["sclc","nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":["pm8002"],"companies":["biontech"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06616532","phase":"3","setting":"A Multicenter, Open-lable, Randomized Phase III Study of PM8002 in Combination With Paclitaxel Compared With Chemotherapy as Second-line Treatment in Small Cell Lung Cancer","sponsor":"Biotheus","started":"2024-11-13","startedType":"actual","enrolled":404,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06616532/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"},{"id":"sclc","kind":"cancer","name":"Small-cell lung cancer","route":"/cancers/sclc/"}],"drug":[{"id":"pm8002","kind":"drug","name":"PM8002","route":"/drugs/pm8002/"}],"company":[{"id":"biontech","kind":"company","name":"BioNTech","route":"/companies/biontech/"}]}}