{"entity":{"id":"nct06612151","kind":"trial","name":"A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer（TAISHAN-302）","aka":["TAISHAN-302"],"tldr":"A phase 3 trial testing YL201 in non-small-cell lung cancer, active and no longer recruiting.","summary":"A Phase III Study of YL201 in Relapsed Small Cell Lung Cancer（TAISHAN-302） is a phase 3 interventional study registered as NCT06612151, led by MediLink Therapeutics (Suzhou), and active but no longer recruiting on the registry. Official title: A Multicenter, Randomised, Controlled, Open-label, Phase III Study to Compare the Efficacy and Safety of YL201 Versus Topotecan Hydrochloride in Subjects With Relapsed Small Cell Lung Cancer. Planned enrolment is 438 participants (estimated). The study started in 2024-12-17 and primary completion is expected in 2027-12-01. No results have been posted on ClinicalTrials.gov.","status":"active","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT06612151","url":"https://clinicaltrials.gov/study/NCT06612151"}],"tags":["ctgov-ingest"],"related":[],"cancers":["nsclc"],"sections":[],"technologies":[],"targets":[],"drugs":["yl201"],"companies":["medilink"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-nct06612151-n-engl-j-med-2026"],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06612151","phase":"3","setting":"A Multicenter, Randomized, Controlled, Open-label, Phase III Study to Compare the Efficacy and Safety of YL201 Versus Topotecan Hydrochloride in Subjects With Relapsed Small Cell Lung Cancer","sponsor":"MediLink Therapeutics (Suzhou)","started":"2024-12-17","startedType":"actual","enrolled":438,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06612151/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"drug":[{"id":"yl201","kind":"drug","name":"YL201","route":"/drugs/yl201/"}],"company":[{"id":"medilink","kind":"company","name":"MediLink Therapeutics","route":"/companies/medilink/"}],"paper":[{"id":"paper-nct06612151-n-engl-j-med-2026","kind":"paper","name":"Tambotatug Pelitecan in Small-Cell Lung Cancer after Platinum-Based Therapy","route":"/key-papers/paper-nct06612151-n-engl-j-med-2026/"}]}}