{"entity":{"id":"nct06105619","kind":"trial","name":"A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).","aka":[],"tldr":"A phase 2/3 trial of Vebreltinib run by Beijing Pearl Biotechnology Limited Liability Company, active.","summary":"A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN). is a phase 2/3 interventional study registered as NCT06105619 by Beijing Pearl Biotechnology Limited Liability Company, with 84 participants enrolled, started 2018-10-08. Conditions listed: Glioblastoma. No results are recorded here; the registry entry is the source.","status":"active","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT06105619","url":"https://clinicaltrials.gov/study/NCT06105619"}],"tags":["ctgov-ingest"],"related":[],"cancers":["glioblastoma","idh-mutant-astrocytoma"],"sections":[],"technologies":["kinase-inhibitors"],"targets":[],"drugs":["vebreltinib"],"companies":["beijing-pearl-biotechnology-limited-liability-company"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT06105619","phase":"2/3","setting":"A Randomized, Controlled, Open, Multicenter, Phase II/III Clinical Study to Evaluate the Safety and Efficacy of Vebreltinib Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN).","sponsor":"Beijing Pearl Biotechnology Limited Liability Company","started":"2018-10-08","startedType":"actual","enrolled":84,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct06105619/","neighbours":{"cancer":[{"id":"idh-mutant-astrocytoma","kind":"cancer","name":"Astrocytoma, IDH-mutant (grades 2 to 4)","route":"/cancers/idh-mutant-astrocytoma/"},{"id":"glioblastoma","kind":"cancer","name":"Glioma & glioblastoma","route":"/cancers/glioblastoma/"}],"technology":[{"id":"kinase-inhibitors","kind":"technology","name":"Small-molecule kinase inhibitors","route":"/technologies/kinase-inhibitors/"}],"drug":[{"id":"vebreltinib","kind":"drug","name":"Vebreltinib","route":"/drugs/vebreltinib/"}],"company":[{"id":"beijing-pearl-biotechnology-limited-liability-company","kind":"company","name":"Beijing Pearl Biotechnology Limited Liability Company","route":"/companies/beijing-pearl-biotechnology-limited-liability-company/"}]}}