{"entity":{"id":"nct05945901","kind":"trial","name":"A Phase II/III Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer","aka":[],"tldr":"A phase 2/3 trial testing HR070803 in colorectal cancer, active and no longer recruiting.","summary":"A Phase II/III Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer is a phase 2/3 interventional study registered as NCT05945901, led by Jiangsu HengRui Medicine, and active but no longer recruiting on the registry. Official title: A Phase II/III, Double-blind, Randomised, Multi-centre Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer. Planned enrolment is 669 participants (actual). The study started in 2023-08-14 and primary completion is expected in 2025-12-01. No results have been posted on ClinicalTrials.gov.","status":"active","asOf":"2026-09-11","links":[{"label":"ClinicalTrials.gov NCT05945901","url":"https://clinicaltrials.gov/study/NCT05945901"}],"tags":["ctgov-ingest"],"related":[],"cancers":["colorectal"],"sections":[],"technologies":[],"targets":[],"drugs":["hr070803"],"companies":["hengrui"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT05945901","phase":"2/3","setting":"A Phase II/III, Double-blind, Randomized, Multi-center Study of HR070803 in Combination With Oxaliplatin, 5-fluorouracil, Calcium Folinate and Bevacizumab Versus FOLFOX in Combination With Bevacizumab for First-line Treatment of Advanced Colorectal Cancer","sponsor":"Jiangsu HengRui Medicine","started":"2023-08-14","startedType":"actual","enrolled":669,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct05945901/","neighbours":{"cancer":[{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"}],"drug":[{"id":"hr070803","kind":"drug","name":"HR070803","route":"/drugs/hr070803/"}],"company":[{"id":"hengrui","kind":"company","name":"Jiangsu Hengrui Pharmaceuticals","route":"/companies/hengrui/"}]}}