{"entity":{"id":"nct02332668","kind":"trial","name":"A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)","aka":["KEYNOTE-051"],"tldr":"A phase 1/2 trial of Pembrolizumab in melanoma and hodgkin lymphoma, run by Merck Sharp & Dohme LLC, now recruiting.","summary":"A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051) is a phase 1/2 interventional study registered as NCT02332668 by Merck Sharp & Dohme LLC, with 370 participants planned, started 2015-03-19 and due to reach its primary completion in 2028-02-02. Interventions recorded: Pembrolizumab. Conditions listed: Melanoma, Lymphoma, Solid Tumor, Classical Hodgkin Lymphoma. No results are recorded here; the registry entry is the source.","status":"recruiting","asOf":"2026-09-16","links":[{"label":"ClinicalTrials.gov NCT02332668","url":"https://clinicaltrials.gov/study/NCT02332668"}],"tags":["ctgov-ingest"],"related":[],"cancers":["melanoma","hodgkin-lymphoma","advanced-melanoma"],"sections":[],"technologies":["checkpoint-inhibitor"],"targets":[],"drugs":["pembrolizumab"],"companies":["merck"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":["paper-nct02332668-lancet-oncol-2020"],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT02332668","phase":"1/2","setting":"A Phase I/II Study of Pembrolizumab (MK-3475) in Children With Advanced Melanoma or a PD-L1 Positive Advanced, Relapsed or Refractory Solid Tumor or Lymphoma (KEYNOTE-051)","sponsor":"Merck Sharp & Dohme LLC","started":"2015-03-19","startedType":"actual","enrolled":370,"enrolledBasis":"registry","outcomes":[]},"route":"/trials/nct02332668/","neighbours":{"cancer":[{"id":"advanced-melanoma","kind":"cancer","name":"Advanced melanoma (unresectable stage III and stage IV)","route":"/cancers/advanced-melanoma/"},{"id":"hodgkin-lymphoma","kind":"cancer","name":"Hodgkin lymphoma","route":"/cancers/hodgkin-lymphoma/"},{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"}],"technology":[{"id":"checkpoint-inhibitor","kind":"technology","name":"Immune checkpoint inhibitors","route":"/technologies/checkpoint-inhibitor/"}],"drug":[{"id":"pembrolizumab","kind":"drug","name":"Pembrolizumab","route":"/drugs/pembrolizumab/"}],"company":[{"id":"merck","kind":"company","name":"Merck & Co. (MSD)","route":"/companies/merck/"}],"paper":[{"id":"paper-nct02332668-lancet-oncol-2020","kind":"paper","name":"Pembrolizumab in paediatric patients with advanced melanoma or a PD-L1-positive, advanced, relapsed, or refractory solid tumour or lymphoma (KEYNOTE-051): interim analysis of an open-label, single-arm, phase 1-2 trial","route":"/key-papers/paper-nct02332668-lancet-oncol-2020/"}]}}