{"entity":{"id":"nct00343382","kind":"trial","name":"Pilocarpine in Treating Vaginal Dryness in Patients With Breast Cancer","aka":[],"tldr":"A phase 3 trial of Pilocarpine in Breast cancer, run by Alliance for Clinical Trials in Oncology, completed.","summary":"Pilocarpine in Treating Vaginal Dryness in Patients With Breast Cancer is a phase 3 interventional study registered as NCT00343382 by Alliance for Clinical Trials in Oncology, with 201 participants recorded, started 2006-12 and reaching its primary completion in 2009-07. Interventions recorded: pilocarpine hydrochloride, placebo. Conditions recorded: Breast Cancer, Vaginal Dryness.\n\nLinked to the drug Pilocarpine because the registry names it among its interventions and Breast cancer among its conditions. Registry record only: no result has been read by an editor.","status":"completed","asOf":"2026-09-24","links":[{"label":"ClinicalTrials.gov NCT00343382","url":"https://clinicaltrials.gov/study/NCT00343382"}],"tags":["pipeline","ctgov-ingest"],"related":[],"cancers":["breast-cancer"],"sections":[],"technologies":[],"targets":[],"drugs":["pilocarpine"],"companies":["alliance-oncology"],"institutions":[],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"nct":"NCT00343382","phase":"3","setting":"Pilocarpine for Vaginal Dryness: A Phase III Randomized, Double Blind, Placebo-Controlled Study","sponsor":"Alliance for Clinical Trials in Oncology","started":"2006-12","yearReported":2014,"enrolled":201,"enrolledBasis":"registry","outcomes":[{"endpoint":"Average Vaginal Dryness Scores Via Area Under the Curve (AUC) Summary Statistics","primary":true,"unit":"units on a scale","arms":[{"name":"Collective Placebo","n":61,"value":63.6,"note":"SD 24.04; Figures from the ClinicalTrials.gov results section (first posted 2014-09-30), not from a publication"},{"name":"Pilocarpine 2 Times Per Day","n":61,"value":55.8,"note":"SD 27.69"},{"name":"Pilocarpine 4 Times Per Day","n":55,"value":66,"note":"SD 21.38"}],"source":"https://clinicaltrials.gov/study/NCT00343382?tab=results"}]},"route":"/trials/nct00343382/","neighbours":{"cancer":[{"id":"breast-cancer","kind":"cancer","name":"Breast cancer (all types)","route":"/cancers/breast-cancer/"}],"drug":[{"id":"pilocarpine","kind":"drug","name":"Pilocarpine","route":"/drugs/pilocarpine/"}],"company":[{"id":"alliance-oncology","kind":"company","name":"Alliance for Clinical Trials in Oncology","route":"/companies/alliance-oncology/"}]}}