{"entity":{"id":"nccs","kind":"institution","name":"National Cancer Centre Singapore","aka":["NCCS","SingHealth Duke-NUS Oncology Academic Clinical Programme"],"tldr":"Singapore's national cancer centre and the largest cancer facility in the country, with a proton centre and leading Asian research in liver and lung cancer genomics.","summary":"The National Cancer Centre Singapore opened in 1999 and moved into a new purpose-built building on the Outram campus in 2023 that houses South-east Asia's first hospital-based proton therapy centre (Goh Cheng Liang Proton Therapy Centre). It treats the majority of Singapore's public-sector cancer patients and, with Duke-NUS Medical School and the Genome Institute of Singapore, has produced influential research on Asian lung cancer in never-smokers, hepatocellular carcinoma and cholangiocarcinoma genomics (including the liver-fluke associated cholangiocarcinoma genome), nasopharyngeal cancer and cancer immunotherapy. NCCS runs the Singapore Translational Cancer Consortium, a large phase 1 unit, and cell therapy programmes with the Singapore Immunology Network, and it coordinates national screening and survivorship initiatives.","asOf":"2026-09-09","wikipedia":"https://en.wikipedia.org/wiki/National_Cancer_Centre_Singapore","links":[{"label":"National Cancer Centre Singapore","url":"https://www.nccs.com.sg"},{"label":"Duke-NUS Medical School","url":"https://www.duke-nus.edu.sg"},{"label":"SingHealth","url":"https://www.singhealth.com.sg"},{"label":"PTCOG: particle therapy facilities in operation","url":"https://www.ptcog.site/index.php/facilities-in-operation-public"}],"tags":[],"related":[],"cancers":["nsclc","hcc","cholangiocarcinoma","head-and-neck","colorectal"],"sections":["radiation","diagnostics","cell-therapy"],"technologies":["proton-therapy","wes-wgs","car-t","til-therapy","proton-therapy-systems"],"targets":["egfr","fgfr2","idh"],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["mutational-signature"],"trials":[],"people":["goh-cheng-liang","lim-soon-thye","rebecca-dent"],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"city":"Singapore","country":"SG","lat":1.28,"lng":103.836,"institutionType":"cancer-center","website":"https://www.nccs.com.sg","university":"Duke-NUS Medical School","programs":["Proton therapy","Asian lung and liver cancer genomics","Phase 1 unit","Cholangiocarcinoma research","Cell therapy"]},"route":"/institutions/nccs/","neighbours":{"cancer":[{"id":"cholangiocarcinoma","kind":"cancer","name":"Biliary tract cancer (cholangiocarcinoma)","route":"/cancers/cholangiocarcinoma/"},{"id":"colorectal","kind":"cancer","name":"Colorectal cancer","route":"/cancers/colorectal/"},{"id":"head-and-neck","kind":"cancer","name":"Head and neck squamous cell carcinoma","route":"/cancers/head-and-neck/"},{"id":"hcc","kind":"cancer","name":"Hepatocellular carcinoma","route":"/cancers/hcc/"},{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"section":[{"id":"cell-therapy","kind":"section","name":"Cell Therapy","route":"/fronts/cell-therapy/"},{"id":"diagnostics","kind":"section","name":"Diagnostics & Biomarkers","route":"/fronts/diagnostics/"},{"id":"radiation","kind":"section","name":"Radiation Therapy","route":"/fronts/radiation/"}],"technology":[{"id":"car-t","kind":"technology","name":"CAR-T cell therapy","route":"/technologies/car-t/"},{"id":"proton-therapy","kind":"technology","name":"Proton therapy","route":"/technologies/proton-therapy/"},{"id":"proton-therapy-systems","kind":"technology","name":"Proton therapy machines: cyclotrons, synchrotrons and single-room systems","route":"/technologies/proton-therapy-systems/"},{"id":"til-therapy","kind":"technology","name":"TIL therapy","route":"/technologies/til-therapy/"},{"id":"wes-wgs","kind":"technology","name":"Whole-exome & whole-genome sequencing","route":"/technologies/wes-wgs/"}],"target":[{"id":"egfr","kind":"target","name":"EGFR","route":"/targets/egfr/"},{"id":"fgfr2","kind":"target","name":"FGFR2","route":"/targets/fgfr2/"},{"id":"idh","kind":"target","name":"IDH1 / IDH2","route":"/targets/idh/"}],"term":[{"id":"mutational-signature","kind":"term","name":"Mutational signature","route":"/terms/mutational-signature/"}],"person":[{"id":"goh-cheng-liang","kind":"person","name":"Goh Cheng Liang","route":"/people/goh-cheng-liang/"},{"id":"lim-soon-thye","kind":"person","name":"Lim Soon Thye","route":"/people/lim-soon-thye/"},{"id":"rebecca-dent","kind":"person","name":"Rebecca Dent","route":"/people/rebecca-dent/"}],"paper":[{"id":"paper-chen-east-asian-lung-adenocarcinoma-nat-genet-2020","kind":"paper","name":"Genomic landscape of lung adenocarcinoma in East Asians","route":"/key-papers/paper-chen-east-asian-lung-adenocarcinoma-nat-genet-2020/"}],"company":[{"id":"hitachi","kind":"company","name":"Hitachi (particle therapy)","route":"/companies/hitachi/"}]}}