{"entity":{"id":"nathan-cherny","kind":"person","name":"Nathan Cherny","aka":[],"tldr":"Created the ESMO Magnitude of Clinical Benefit Scale, the standard tool for grading how much a cancer drug really helps.","summary":"Nathan Cherny is Director of Cancer Pain and Palliative Medicine at Shaare Zedek Medical Center in Jerusalem and Chair of the ESMO-MCBS Working Group of the European Society for Medical Oncology (ESMO). His specialisms are palliative medicine, value assessment of cancer drugs and ethics. He created the ESMO Magnitude of Clinical Benefit Scale, which grades trial results by the size of the benefit they show and is used by health systems worldwide as the standard tool for judging how much a cancer drug really helps. His Annals of Oncology paper described this standardised, validated approach to stratifying clinical benefit. His publications are listed on PubMed.","asOf":"2026-09-08","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Cherny%20NI%5BAuthor%5D%20ESMO-MCBS"}],"tags":[],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["esmo"],"pathways":[],"terms":["standard-of-care"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Director, Cancer Pain and Palliative Medicine, Shaare Zedek Medical Center; Chair, ESMO-MCBS Working Group","institutionId":"esmo","specialisms":["Palliative medicine","Value assessment of cancer drugs","Ethics"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Cherny%20NI%5BAuthor%5D%20ESMO-MCBS"}],"papers":[{"title":"A standardised, generic, validated approach to stratify the magnitude of clinical benefit that can be anticipated from anti-cancer therapies: the ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS)","journal":"Annals of Oncology","year":2015,"doi":"10.1093/annonc/mdv249"}]},"route":"/people/nathan-cherny/","neighbours":{"institution":[{"id":"esmo","kind":"institution","name":"European Society for Medical Oncology (ESMO)","route":"/institutions/esmo/"},{"id":"shaare-zedek","kind":"institution","name":"Shaare Zedek Medical Center","route":"/institutions/shaare-zedek/"}],"term":[{"id":"standard-of-care","kind":"term","name":"Standard of care","route":"/terms/standard-of-care/"}],"idea":[{"id":"idea-tr1-power-for-meaningful-benefit","kind":"idea","name":"Power trials to detect a benefit patients would value, not the smallest detectable one","route":"/ideas/idea-tr1-power-for-meaningful-benefit/"},{"id":"idea-bio2-cachexia-pathway-code","kind":"idea","name":"Treat wasting like sepsis: a trigger, a bundle, an audit","route":"/ideas/idea-bio2-cachexia-pathway-code/"},{"id":"idea-tr1-win-ratio-net-benefit-endpoint","kind":"idea","name":"Win-ratio endpoints that weigh survival, toxicity and quality of life together","route":"/ideas/idea-tr1-win-ratio-net-benefit-endpoint/"}]}}