{"entity":{"id":"mitsuru-sasako","kind":"person","name":"Mitsuru Sasako","aka":[],"tldr":"Japanese surgeon whose JCOG trials defined D2 gastrectomy and adjuvant S-1 as standards for gastric cancer.","summary":"Mitsuru Sasako (Tokyo and Hyogo) led the JCOG 9501 trial showing that extended para-aortic nodal dissection adds nothing to D2 gastrectomy, and co-led the ACTS-GC trial that established adjuvant S-1 after D2 surgery in Japan. His surgical standards and training work underpin the D2 approach now recommended in Western guidelines. He remains an advisor to international gastric cancer surgical trials.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Sasako%20M%5BAuthor%5D%20gastric%20D2"}],"tags":["gastric","surgery","japan"],"related":[],"cancers":["gastric"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":[],"pathways":[],"terms":["gastrectomy","lymphadenectomy"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Professor Emeritus, Hyogo College of Medicine; former Chief of Gastric Surgery, National Cancer Center Hospital Tokyo","specialisms":["Gastric cancer surgery","D2 lymphadenectomy","Adjuvant therapy","Surgical trials"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Sasako%20M%5BAuthor%5D%20gastric%20D2"}],"papers":[{"title":"D2 lymphadenectomy alone or with para-aortic nodal dissection for gastric cancer (JCOG 9501)","journal":"NEJM","year":2008,"doi":"10.1056/NEJMoa0707035"},{"title":"Five-year outcomes of a randomized phase III trial comparing adjuvant chemotherapy with S-1 versus surgery alone in stage II or III gastric cancer (ACTS-GC)","journal":"JCO","year":2011,"doi":"10.1200/JCO.2011.36.5908"}]},"route":"/people/mitsuru-sasako/","neighbours":{"cancer":[{"id":"gastric","kind":"cancer","name":"Gastric & gastro-oesophageal junction cancer","route":"/cancers/gastric/"}],"term":[{"id":"gastrectomy","kind":"term","name":"Gastrectomy","route":"/terms/gastrectomy/"},{"id":"lymphadenectomy","kind":"term","name":"Lymphadenectomy (lymph node dissection)","route":"/terms/lymphadenectomy/"}]}}