{"entity":{"id":"michael-taylor","kind":"person","name":"Michael D. Taylor","aka":[],"tldr":"Neurosurgeon-scientist who defined the four molecular subgroups of medulloblastoma that now guide therapy.","summary":"Michael Taylor led the international consensus that divided medulloblastoma into WNT, SHH, Group 3 and Group 4 subgroups, a classification adopted by the WHO that underpins current risk-stratified and de-escalated treatment trials. His laboratory showed that medulloblastoma metastases diverge genetically from the primary tumour and that the tumours spread via blood. He moved from SickKids Toronto to Texas Children's in 2023.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Taylor%20MD%5BAuthor%5D%20medulloblastoma"}],"tags":["paediatric","medulloblastoma","genomics"],"related":[],"cancers":["medulloblastoma"],"sections":[],"technologies":["methylation-profiling","wes-wgs"],"targets":[],"drugs":[],"companies":[],"institutions":["texas-childrens"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["cancer-cell"],"dependsOn":[],"notes":[],"role":"Professor of Pediatrics and Neurosurgery, Baylor College of Medicine and Texas Children's Hospital","institutionId":"texas-childrens","specialisms":["Medulloblastoma","Paediatric neurosurgery","Brain tumour genomics","Metastasis biology"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Taylor%20MD%5BAuthor%5D%20medulloblastoma"}],"papers":[{"title":"Molecular subgroups of medulloblastoma: the current consensus","journal":"Acta Neuropathologica","year":2012,"doi":"10.1007/s00401-011-0922-z"},{"title":"Intertumoral heterogeneity within medulloblastoma subgroups","journal":"Cancer Cell","year":2017,"doi":"10.1016/j.ccell.2017.05.005"}]},"route":"/people/michael-taylor/","neighbours":{"cancer":[{"id":"medulloblastoma","kind":"cancer","name":"Medulloblastoma","route":"/cancers/medulloblastoma/"}],"technology":[{"id":"methylation-profiling","kind":"technology","name":"DNA methylation profiling","route":"/technologies/methylation-profiling/"},{"id":"wes-wgs","kind":"technology","name":"Whole-exome & whole-genome sequencing","route":"/technologies/wes-wgs/"}],"institution":[{"id":"texas-childrens","kind":"institution","name":"Texas Children's Cancer and Hematology Center","route":"/institutions/texas-childrens/"}],"journal":[{"id":"cancer-cell","kind":"journal","name":"Cancer Cell","route":"/journals/cancer-cell/"}]}}