{"entity":{"id":"michael-caligiuri","kind":"person","name":"Michael A. Caligiuri","aka":[],"tldr":"Michael Caligiuri is an NK cell immunologist and past AACR president who leads City of Hope's hospital.","summary":"Michael Caligiuri is President of City of Hope National Medical Center, Deana and Steve Campbell Physician-in-Chief, and Treasurer of the American Association for Cancer Research (AACR), of which he is a past president. A physician-scientist specialising in natural killer cells, leukaemia and immunotherapy, he is known for work on natural killer cell biology, IL-15 and NK-based immunotherapy, and formerly directed Ohio State's cancer centre. His papers include a Blood review of human natural killer cells and a Blood study showing CD56bright natural killer cells in human lymph nodes are activated by T cell-derived IL-2, linking adaptive and innate immunity. His work bears on acute myeloid leukaemia, CAR-NK therapy and engineered cytokines.","asOf":"2026-09-08","wikipedia":"https://en.wikipedia.org/wiki/Michael_A._Caligiuri","links":[{"label":"City of Hope research faculty","url":"https://www.cityofhope.org/research/find-a-researcher"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Caligiuri%20MA%5BAuthor%5D"},{"label":"Google Scholar","url":"https://scholar.google.com/scholar?q=Michael%20A.%20Caligiuri"}],"tags":[],"related":[],"cancers":["aml"],"sections":[],"technologies":["car-nk-macrophage","cytokine-therapy"],"targets":[],"drugs":[],"companies":[],"institutions":["city-of-hope","aacr"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"President, City of Hope National Medical Center; Deana and Steve Campbell Physician-in-Chief; AACR Treasurer","institutionId":"city-of-hope","specialisms":["Natural killer cells","Leukaemia","Immunotherapy"],"profiles":[{"label":"City of Hope research faculty","url":"https://www.cityofhope.org/research/find-a-researcher"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Caligiuri%20MA%5BAuthor%5D"},{"label":"Google Scholar","url":"https://scholar.google.com/scholar?q=Michael%20A.%20Caligiuri"}],"papers":[{"title":"Human natural killer cells","journal":"Blood","year":2008,"url":"https://doi.org/10.1182/blood-2007-09-077438","doi":"10.1182/blood-2007-09-077438"},{"title":"CD56bright natural killer cells are present in human lymph nodes and are activated by T cell-derived IL-2: a potential new link between adaptive and innate immunity","journal":"Blood","year":2003,"url":"https://doi.org/10.1182/blood-2002-09-2876","doi":"10.1182/blood-2002-09-2876"}]},"route":"/people/michael-caligiuri/","neighbours":{"cancer":[{"id":"aml","kind":"cancer","name":"Acute myeloid leukaemia","route":"/cancers/aml/"}],"technology":[{"id":"car-nk-macrophage","kind":"technology","name":"CAR-NK & CAR-macrophage","route":"/technologies/car-nk-macrophage/"},{"id":"cytokine-therapy","kind":"technology","name":"Cytokines & engineered cytokines","route":"/technologies/cytokine-therapy/"}],"institution":[{"id":"aacr","kind":"institution","name":"American Association for Cancer Research (AACR)","route":"/institutions/aacr/"},{"id":"city-of-hope","kind":"institution","name":"City of Hope","route":"/institutions/city-of-hope/"},{"id":"osu-james","kind":"institution","name":"The Ohio State University Comprehensive Cancer Center, James Cancer Hospital and Solove Research Institute","route":"/institutions/osu-james/"}]}}