{"entity":{"id":"maximilian-diehn","kind":"person","name":"Maximilian Diehn","aka":[],"tldr":"Radiation oncologist who showed a blood test can detect leftover lung cancer months before scans.","summary":"Maximilian Diehn is Professor of Radiation Oncology at Stanford University, within the Stanford Cancer Institute. A radiation oncologist and physician-scientist specialising in circulating tumour DNA and lung cancer, he co-developed CAPP-Seq with Ash Alizadeh and demonstrated ctDNA-based detection of minimal residual disease after curative lung cancer treatment, showing a blood test can find leftover cancer months before scans. His papers include the Cancer Discovery report on early detection of molecular residual disease in localised lung cancer by ctDNA profiling and a Nature study integrating genomic features for non-invasive early lung cancer detection. He also studies radiation biology, personalised radiotherapy and stereotactic techniques in non-small-cell lung cancer.","asOf":"2026-09-08","wikipedia":"https://en.wikipedia.org/wiki/Maximilian_Diehn","links":[{"label":"Stanford profile","url":"https://profiles.stanford.edu/search?q=Maximilian%20Diehn"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Diehn%20M%5BAuthor%5D"},{"label":"Google Scholar","url":"https://scholar.google.com/scholar?q=Maximilian%20Diehn"}],"tags":[],"related":[],"cancers":["nsclc"],"sections":[],"technologies":["mrd-testing","liquid-biopsy","sbrt"],"targets":[],"drugs":[],"companies":[],"institutions":["stanford"],"pathways":[],"terms":["mrd"],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Professor of Radiation Oncology, Stanford University","institutionId":"stanford","specialisms":["Radiation oncology","Circulating tumour DNA","Lung cancer"],"profiles":[{"label":"Stanford profile","url":"https://profiles.stanford.edu/search?q=Maximilian%20Diehn"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Diehn%20M%5BAuthor%5D"},{"label":"Google Scholar","url":"https://scholar.google.com/scholar?q=Maximilian%20Diehn"}],"papers":[{"title":"Early Detection of Molecular Residual Disease in Localized Lung Cancer by Circulating Tumor DNA Profiling","journal":"Cancer Discovery","year":2017,"url":"https://doi.org/10.1158/2159-8290.CD-17-0716","doi":"10.1158/2159-8290.CD-17-0716"},{"title":"Integrating genomic features for non-invasive early lung cancer detection","journal":"Nature","year":2020,"url":"https://doi.org/10.1038/s41586-020-2140-0","doi":"10.1038/s41586-020-2140-0"}],"orcid":"0000-0003-2032-0581"},"route":"/people/maximilian-diehn/","neighbours":{"cancer":[{"id":"nsclc","kind":"cancer","name":"Non-small-cell lung cancer","route":"/cancers/nsclc/"}],"technology":[{"id":"liquid-biopsy","kind":"technology","name":"Liquid biopsy (ctDNA)","route":"/technologies/liquid-biopsy/"},{"id":"mrd-testing","kind":"technology","name":"MRD / molecular residual disease testing","route":"/technologies/mrd-testing/"},{"id":"sbrt","kind":"technology","name":"SBRT / SABR (stereotactic radiotherapy)","route":"/technologies/sbrt/"}],"institution":[{"id":"stanford","kind":"institution","name":"Stanford Health Care / Stanford Cancer Institute","route":"/institutions/stanford/"}],"term":[{"id":"mrd","kind":"term","name":"Minimal / molecular residual disease (MRD)","route":"/terms/mrd/"}]}}