{"entity":{"id":"matthew-vander-heiden","kind":"person","name":"Matthew Vander Heiden","aka":[],"tldr":"Physician-scientist and cancer metabolism expert who directs MIT's Koch Institute for Integrative Cancer Research.","summary":"Matthew Vander Heiden is Director of the Koch Institute for Integrative Cancer Research at MIT, with scientific, strategic and operational oversight of the institute. His laboratory studies how cell metabolism supports tumour growth, and he is a practising medical oncologist at Dana-Farber Cancer Institute. His 2009 Science review on the Warburg effect is one of the most cited papers in the field.","asOf":"2026-09-10","links":[{"label":"Institution profile","url":"https://ki.mit.edu/people/institute-directorship"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Vander+Heiden+MG%5BAuthor%5D"}],"tags":["leadership","clinician-scientist","cancer metabolism"],"related":[],"cancers":["pancreatic"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["mit-koch"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Director","institutionId":"mit-koch","specialisms":["Cancer metabolism","Medical oncology","Cell biology"],"profiles":[{"label":"Institution profile","url":"https://ki.mit.edu/people/institute-directorship"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Vander+Heiden+MG%5BAuthor%5D"}],"papers":[{"title":"Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation","journal":"Science","year":2009,"url":"https://doi.org/10.1126/science.1160809","doi":"10.1126/science.1160809"}]},"route":"/people/matthew-vander-heiden/","neighbours":{"cancer":[{"id":"pancreatic","kind":"cancer","name":"Pancreatic ductal adenocarcinoma","route":"/cancers/pancreatic/"}],"institution":[{"id":"mit-koch","kind":"institution","name":"David H. Koch Institute for Integrative Cancer Research at MIT","route":"/institutions/mit-koch/"}],"pathway":[{"id":"theories-of-cancer","kind":"pathway","name":"Theories of cancer: how the ideas connect","route":"/pathways/theories-of-cancer/"}],"term":[{"id":"metabolic-theory-of-cancer","kind":"term","name":"Metabolic theory of cancer: from Warburg to oncometabolites","route":"/terms/metabolic-theory-of-cancer/"}]}}