{"entity":{"id":"matthew-hurles","kind":"person","name":"Matthew Hurles","aka":[],"tldr":"Human geneticist who directs the Wellcome Sanger Institute, a world centre for cancer genome research.","summary":"Matthew Hurles is Director of the Wellcome Sanger Institute and a Senior Group Leader there. His own research focuses on identifying disease-causing genetic variants in developmental disorders through large-scale sequencing studies such as Deciphering Developmental Disorders. As Director he oversees the institute's programmes including cancer, ageing and somatic mutation genomics.","asOf":"2026-09-10","links":[{"label":"Institution profile","url":"https://www.sanger.ac.uk/person/hurles-matthew/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Hurles+ME%5BAuthor%5D"}],"tags":["leadership","clinician-scientist","genomics"],"related":[],"cancers":[],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["wellcome-sanger"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["nature-genetics"],"dependsOn":[],"notes":[],"role":"Director of the Wellcome Sanger Institute and Senior Group Leader","institutionId":"wellcome-sanger","specialisms":["Human genetics","Genomic medicine","Developmental disorders"],"profiles":[{"label":"Institution profile","url":"https://www.sanger.ac.uk/person/hurles-matthew/"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Hurles+ME%5BAuthor%5D"}],"papers":[{"title":"Identification of somatically acquired rearrangements in cancer using genome-wide massively parallel paired-end sequencing","journal":"Nature Genetics","year":2008,"doi":"10.1038/ng.128"}],"orcid":"0000-0002-2333-7015"},"route":"/people/matthew-hurles/","neighbours":{"institution":[{"id":"wellcome-sanger","kind":"institution","name":"Wellcome Sanger Institute","route":"/institutions/wellcome-sanger/"}],"journal":[{"id":"nature-genetics","kind":"journal","name":"Nature Genetics","route":"/journals/nature-genetics/"}]}}