{"entity":{"id":"mary-mccormack","kind":"person","name":"Mary McCormack","aka":[],"tldr":"Led INTERLACE, which showed a short course of chemotherapy before chemoradiation cuts cervical cancer deaths using cheap, available drugs.","summary":"Mary McCormack was chief investigator of INTERLACE, the international trial showing six weeks of induction carboplatin and paclitaxel before standard chemoradiotherapy improves progression-free and overall survival in locally advanced cervical cancer, a result immediately implementable in low-resource settings where most cervical cancer occurs. She leads gynaecological radiotherapy research at UCLH.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=McCormack%20M%5BAuthor%5D%20INTERLACE%20cervical"}],"tags":["cervical","chemoradiotherapy","global-health"],"related":[],"cancers":["cervical"],"sections":[],"technologies":["imrt-igrt","brachytherapy"],"targets":[],"drugs":["carboplatin","paclitaxel"],"companies":[],"institutions":["uclh"],"pathways":[],"terms":[],"trials":["interlace"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["british-journal-of-cancer"],"dependsOn":[],"notes":[],"role":"Consultant Clinical Oncologist, University College London Hospitals","institutionId":"uclh","specialisms":["Cervical cancer","Chemoradiotherapy","Induction chemotherapy","Gynaecological radiotherapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=McCormack%20M%5BAuthor%5D%20INTERLACE%20cervical"}],"papers":[{"title":"Induction chemotherapy followed by standard chemoradiotherapy versus standard chemoradiotherapy alone in patients with locally advanced cervical cancer (GCIG INTERLACE)","journal":"Lancet","year":2024,"doi":"10.1016/S0140-6736(24)01438-7"},{"title":"A phase II study of weekly neoadjuvant chemotherapy followed by radical chemoradiation for locally advanced cervical cancer","journal":"British Journal of Cancer","year":2013,"doi":"10.1038/bjc.2013.230"}]},"route":"/people/mary-mccormack/","neighbours":{"cancer":[{"id":"cervical","kind":"cancer","name":"Cervical cancer","route":"/cancers/cervical/"}],"technology":[{"id":"brachytherapy","kind":"technology","name":"Brachytherapy","route":"/technologies/brachytherapy/"},{"id":"imrt-igrt","kind":"technology","name":"IMRT / IGRT (modern external beam)","route":"/technologies/imrt-igrt/"}],"drug":[{"id":"carboplatin","kind":"drug","name":"Carboplatin","route":"/drugs/carboplatin/"},{"id":"paclitaxel","kind":"drug","name":"Paclitaxel / nab-paclitaxel","route":"/drugs/paclitaxel/"}],"institution":[{"id":"uclh","kind":"institution","name":"University College London Hospitals / UCL Cancer Institute","route":"/institutions/uclh/"}],"trial":[{"id":"interlace","kind":"trial","name":"INTERLACE","route":"/trials/interlace/"}],"journal":[{"id":"british-journal-of-cancer","kind":"journal","name":"British Journal of Cancer","route":"/journals/british-journal-of-cancer/"}]}}