{"entity":{"id":"mark-faries","kind":"person","name":"Mark B. Faries","aka":[],"tldr":"Surgeon who led MSLT-II, showing that removing all lymph nodes after a positive sentinel node does not improve melanoma survival.","summary":"Mark Faries was principal investigator of MSLT-II, the randomised trial showing completion lymph node dissection after a positive sentinel node biopsy does not improve melanoma-specific survival, which ended routine completion dissection worldwide, and a senior investigator of MSLT-I with Donald Morton. He leads surgical aspects of neoadjuvant immunotherapy trials and the melanoma programme at the Angeles Clinic.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Faries%20MB%5BAuthor%5D%20melanoma%20sentinel"}],"tags":["melanoma","surgery","de-escalation"],"related":[],"cancers":["melanoma"],"sections":[],"technologies":["sentinel-node"],"targets":[],"drugs":[],"companies":[],"institutions":["cedars-sinai-cancer"],"pathways":[],"terms":[],"trials":["mslt-ii"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Co-Director, Melanoma Program, The Angeles Clinic and Research Institute, Cedars-Sinai","institutionId":"cedars-sinai-cancer","specialisms":["Melanoma surgery","Sentinel node biopsy","Surgical oncology","Neoadjuvant therapy"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Faries%20MB%5BAuthor%5D%20melanoma%20sentinel"}],"papers":[{"title":"Completion dissection or observation for sentinel-node metastasis in melanoma (MSLT-II)","journal":"NEJM","year":2017,"doi":"10.1056/NEJMoa1613210"},{"title":"Final trial report of sentinel-node biopsy versus nodal observation in melanoma (MSLT-I)","journal":"NEJM","year":2014,"doi":"10.1056/NEJMoa1310460"}],"orcid":"0000-0003-1752-7282"},"route":"/people/mark-faries/","neighbours":{"cancer":[{"id":"melanoma","kind":"cancer","name":"Melanoma","route":"/cancers/melanoma/"}],"technology":[{"id":"sentinel-node","kind":"technology","name":"Sentinel lymph node biopsy","route":"/technologies/sentinel-node/"}],"institution":[{"id":"cedars-sinai-cancer","kind":"institution","name":"Cedars-Sinai Cancer","route":"/institutions/cedars-sinai-cancer/"}],"trial":[{"id":"mslt-ii","kind":"trial","name":"MSLT-II","route":"/trials/mslt-ii/"}]}}