{"entity":{"id":"mark-emberton","kind":"person","name":"Mark Emberton","aka":[],"tldr":"Urologist behind PROMIS and PRECISION, which put MRI before biopsy in the prostate cancer pathway.","summary":"Mark Emberton was senior investigator of PROMIS and PRECISION, the trials showing that multiparametric MRI before biopsy detects more clinically significant prostate cancers and fewer insignificant ones than standard systematic biopsy, which rewrote diagnostic guidelines worldwide. He pioneered focal therapy with HIFU and cryotherapy and leads interventional oncology research at UCL.","asOf":"2026-09-10","wikipedia":"https://en.wikipedia.org/wiki/Mark_Emberton","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Emberton%20M%5BAuthor%5D%20prostate%20MRI"}],"tags":["prostate","imaging","focal-therapy"],"related":[],"cancers":["prostate"],"sections":[],"technologies":["mri","hifu-histotripsy"],"targets":[],"drugs":[],"companies":[],"institutions":["uclh"],"pathways":[],"terms":[],"trials":["precision-mri"],"people":[],"bottlenecks":[],"keyPapers":[],"journals":[],"dependsOn":[],"notes":[],"role":"Professor of Interventional Oncology and Dean of the Faculty of Medical Sciences, University College London","institutionId":"uclh","specialisms":["Prostate cancer diagnostics","MRI-guided biopsy","Focal therapy","Interventional oncology"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Emberton%20M%5BAuthor%5D%20prostate%20MRI"}],"papers":[{"title":"MRI-targeted or standard biopsy for prostate-cancer diagnosis (PRECISION)","journal":"NEJM","year":2018,"doi":"10.1056/NEJMoa1801993"},{"title":"Diagnostic accuracy of multi-parametric MRI and TRUS biopsy in prostate cancer (PROMIS)","journal":"Lancet","year":2017,"doi":"10.1016/S0140-6736(16)32401-1"}],"orcid":"0000-0003-4230-0338"},"route":"/people/mark-emberton/","neighbours":{"cancer":[{"id":"prostate","kind":"cancer","name":"Prostate cancer","route":"/cancers/prostate/"}],"technology":[{"id":"hifu-histotripsy","kind":"technology","name":"Focused ultrasound & histotripsy","route":"/technologies/hifu-histotripsy/"},{"id":"mri","kind":"technology","name":"MRI","route":"/technologies/mri/"}],"institution":[{"id":"uclh","kind":"institution","name":"University College London Hospitals / UCL Cancer Institute","route":"/institutions/uclh/"}],"trial":[{"id":"precision-mri","kind":"trial","name":"PRECISION","route":"/trials/precision-mri/"},{"id":"promis","kind":"trial","name":"PROMIS","route":"/trials/promis/"}],"paper":[{"id":"paper-ahmed-promis-multiparametric-mri-lancet-2017","kind":"paper","name":"PROMIS: diagnostic accuracy of multiparametric MRI and TRUS biopsy in prostate cancer","route":"/key-papers/paper-ahmed-promis-multiparametric-mri-lancet-2017/"}],"person":[{"id":"caroline-moore","kind":"person","name":"Caroline Moore","route":"/people/caroline-moore/"},{"id":"rakesh-heer","kind":"person","name":"Rakesh Heer","route":"/people/rakesh-heer/"}]}}