{"entity":{"id":"marie-catherine-vozenin","kind":"person","name":"Marie-Catherine Vozenin","aka":[],"tldr":"Radiobiologist who discovered the FLASH effect: ultra-fast radiation spares healthy tissue while still killing tumours.","summary":"Marie-Catherine Vozenin led the 2014 study showing that radiation delivered at ultra-high dose rates (over 40 Gy per second) spares normal lung tissue in mice while retaining anti-tumour efficacy, the FLASH effect, and went on to confirm it in mini-pigs, cats and the first human patient with Jean Bourhis. Her work launched a global effort to build FLASH-capable machines and understand the underlying biology.","asOf":"2026-09-10","links":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Vozenin%20MC%5BAuthor%5D%20FLASH"}],"tags":["radiotherapy","flash","radiobiology"],"related":[],"cancers":[],"sections":[],"technologies":["flash-rt"],"targets":[],"drugs":[],"companies":[],"institutions":["hug-geneva","chuv-lausanne"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["science-translational-medicine"],"dependsOn":[],"notes":[],"role":"Head of the Radiotherapy and Radiobiology Laboratory, Geneva University Hospitals; Professor, University of Geneva","institutionId":"hug-geneva","specialisms":["FLASH radiotherapy","Radiobiology","Normal tissue protection","Ultra-high dose rate radiation"],"profiles":[{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Vozenin%20MC%5BAuthor%5D%20FLASH"}],"papers":[{"title":"Ultrahigh dose-rate FLASH irradiation increases the differential response between normal and tumor tissue in mice","journal":"Science Translational Medicine","year":2014,"doi":"10.1126/scitranslmed.3008973"},{"title":"The advantage of FLASH radiotherapy confirmed in mini-pig and cat-cancer patients","journal":"Clinical Cancer Research","year":2019,"doi":"10.1158/1078-0432.CCR-17-3375"}],"orcid":"0000-0002-2109-8073"},"route":"/people/marie-catherine-vozenin/","neighbours":{"technology":[{"id":"flash-rt","kind":"technology","name":"FLASH radiotherapy","route":"/technologies/flash-rt/"}],"institution":[{"id":"hug-geneva","kind":"institution","name":"Geneva University Hospitals (HUG)","route":"/institutions/hug-geneva/"},{"id":"chuv-lausanne","kind":"institution","name":"Lausanne University Hospital (CHUV) / Ludwig Institute Lausanne","route":"/institutions/chuv-lausanne/"}],"journal":[{"id":"science-translational-medicine","kind":"journal","name":"Science Translational Medicine","route":"/journals/science-translational-medicine/"}]}}