{"entity":{"id":"marek-svoboda","kind":"person","name":"Marek Svoboda","aka":[],"tldr":"Medical oncologist who leads the Masaryk Memorial Cancer Institute in Brno, the Czech Republic's largest dedicated cancer centre.","summary":"Prof. Marek Svoboda is General Director of the Masaryk Memorial Cancer Institute (MOU) in Brno. He is a medical oncologist whose research has focused on breast cancer, hereditary cancer syndromes and molecular oncology. Under his leadership MOU operates as a comprehensive cancer centre combining clinical care, research and education.","asOf":"2026-09-10","links":[{"label":"Institution profile","url":"https://www.mou.cz/en/management/t1644"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Svoboda+M%5BAuthor%5D+Brno"}],"tags":["leadership","clinician-scientist","breast cancer","medical oncology"],"related":[],"cancers":["breast-hr-positive","breast-her2-positive"],"sections":[],"technologies":[],"targets":[],"drugs":[],"companies":[],"institutions":["mou-brno"],"pathways":[],"terms":[],"trials":[],"people":[],"bottlenecks":[],"keyPapers":[],"journals":["oncotarget","radiation-oncology"],"dependsOn":[],"notes":[],"role":"General Director","institutionId":"mou-brno","specialisms":["Medical oncology","Breast cancer","Cancer genetics"],"profiles":[{"label":"Institution profile","url":"https://www.mou.cz/en/management/t1644"},{"label":"PubMed","url":"https://pubmed.ncbi.nlm.nih.gov/?term=Svoboda+M%5BAuthor%5D+Brno"}],"papers":[{"title":"MicroRNA expression profile associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer patients","journal":"Radiation Oncology","year":2012,"doi":"10.1186/1748-717x-7-195"},{"title":"Long non-coding RNA ZFAS1 interacts with CDK1 and is involved in p53-dependent cell cycle control and apoptosis in colorectal cancer","journal":"Oncotarget","year":2015,"doi":"10.18632/oncotarget.5807"},{"title":"MiR-215-5p is a tumor suppressor in colorectal cancer targeting EGFR ligand epiregulin and its transcriptional inducer HOXB9","journal":"Oncogenesis","year":2017,"doi":"10.1038/s41389-017-0006-6"}]},"route":"/people/marek-svoboda/","neighbours":{"cancer":[{"id":"breast-her2-positive","kind":"cancer","name":"HER2-positive breast cancer","route":"/cancers/breast-her2-positive/"},{"id":"breast-hr-positive","kind":"cancer","name":"HR-positive / HER2-negative breast cancer","route":"/cancers/breast-hr-positive/"}],"institution":[{"id":"mou-brno","kind":"institution","name":"Masaryk Memorial Cancer Institute","route":"/institutions/mou-brno/"}],"journal":[{"id":"oncotarget","kind":"journal","name":"Oncotarget","route":"/journals/oncotarget/"},{"id":"radiation-oncology","kind":"journal","name":"Radiation oncology","route":"/journals/radiation-oncology/"}]}}